Heme degradation enzyme biliverdin IXβ reductase is required for stem cell glutamine metabolism

Bioenergetic requirements of hematopoietic stem cells and pluripotent stem cells (PSCs) vary with lineage fate, and cellular adaptations rely largely on substrate (glucose/glutamine) availability and mitochondrial function to balance tricarboxylic acid (TCA)-derived anabolic and redox-regulated anti...

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Détails bibliographiques
Publié dans:Biochem J
Auteurs principaux: Li, Zongdong, Nesbitt, Natasha M., Malone, Lisa E., Gnatenko, Dimitri V., Wu, Song, Wang, Daifeng, Zhu, Wei, Girnun, Geoffrey D., Bahou, Wadie F.
Format: Artigo
Langue:Inglês
Publié: 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8278628/
https://ncbi.nlm.nih.gov/pubmed/29500232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20180016
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