Protein/Protein Interactions in the Mammalian Heme Degradation Pathway: HEME OXYGENASE-2, CYTOCHROME P450 REDUCTASE, AND BILIVERDIN REDUCTASE

Heme oxygenase (HO) catalyzes the rate-limiting step in the O(2)-dependent degradation of heme to biliverdin, CO, and iron with electrons delivered from NADPH via cytochrome P450 reductase (CPR). Biliverdin reductase (BVR) then catalyzes conversion of biliverdin to bilirubin. We describe mutagenesis...

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Detalhes bibliográficos
Main Authors: Spencer, Andrea L. M., Bagai, Ireena, Becker, Donald F., Zuiderweg, Erik R. P., Ragsdale, Stephen W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207996/
https://ncbi.nlm.nih.gov/pubmed/25196843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.582783
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