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Human Heme Oxygenase-1 Efficiently Catabolizes Heme in the Absence of Biliverdin Reductase
Heme oxygenase 1 (HO-1) uses molecular oxygen and electrons from NADPH cytochrome P450 reductase to convert heme to CO, ferrous iron, and biliverdin (BV). Enzymatic studies with the purified 30-kDa form of HO-1 routinely use a coupled assay containing biliverdin reductase (BVR), which converts BV to...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2967390/ https://ncbi.nlm.nih.gov/pubmed/20679134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.110.034777 |
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