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Human Heme Oxygenase-1 Efficiently Catabolizes Heme in the Absence of Biliverdin Reductase

Heme oxygenase 1 (HO-1) uses molecular oxygen and electrons from NADPH cytochrome P450 reductase to convert heme to CO, ferrous iron, and biliverdin (BV). Enzymatic studies with the purified 30-kDa form of HO-1 routinely use a coupled assay containing biliverdin reductase (BVR), which converts BV to...

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Xehetasun bibliografikoak
Egile Nagusiak: Reed, James R., Huber, Warren J., Backes, Wayne L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Pharmacology and Experimental Therapeutics 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967390/
https://ncbi.nlm.nih.gov/pubmed/20679134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.110.034777
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