Disease-Associated Particulates and Joint Inflammation; Mechanistic Insights and Potential Therapeutic Targets

by Mahon, Olwyn R., Dunne, Aisling
Published in Front Immunol (2018)

Astrocytes: heterogeneous and dynamic phenotypes in neurodegeneration and innate immunity

by Cunningham, Colm, Dunne, Aisling, Lopez-Rodriguez, Ana Belen
Published in Neuroscientist (2018)

The Role of Macrophages in the Infarcted Myocardium: Orchestrators of ECM Remodeling

by O'Rourke, Sinead A., Dunne, Aisling, Monaghan, Michael G.
Published in Front Cardiovasc Med (2019)

Toll-like Receptor 3 (TLR3) Signaling Requires TLR4 Interactor with Leucine-rich Repeats (TRIL)

by Carpenter, Susan, Wochal, Paulina, Dunne, Aisling, O'Neill, Luke A. J.
Published 2011

Plant-Derived Polyphenols Modulate Human Dendritic Cell Metabolism and Immune Function via AMPK-Dependent Induction of Heme Oxygenase-1

by Campbell, Nicole K., Fitzgerald, Hannah K., Fletcher, Jean M., Dunne, Aisling
Published in Front Immunol (2019)

Osteoarthritis-associated basic calcium phosphate crystals activate membrane proximal kinases in human innate immune cells

by Corr, Emma M., Cunningham, Clare C., Helbert, Laura, McCarthy, Geraldine M., Dunne, Aisling
Published in Arthritis Res Ther (2017)

Activation of biliverdin-IXα reductase by inorganic phosphate and related anions

by Franklin, Edward, Browne, Seamus, Hayes, Jerrard, Boland, Coilin, Dunne, Aisling, Elliot, Gordon, Mantle, Timothy J.
Published 2007

MyD88 adapter-like (Mal) is phosphorylated by Bruton's tyrosine kinase during TLR2 and TLR4 signal transduction.

by Gray, Pearl, Dunne, Aisling, Brikos, Constantinos, Jefferies, Caroline A., Doyle, Sarah L., O′Neill, Luke A. J.
Published in J Biol Chem (2016)

DNA sensors are expressed in astrocytes and microglia in vitro and are upregulated during gliosis in neurodegenerative disease

by Cox, Donal J., Field, Robert H., Williams, David G., Baran, Marcin, Bowie, Andrew G., Cunningham, Colm, Dunne, Aisling
Published in Glia (2015)

IRAK1 and IRAK4 Promote Phosphorylation, Ubiquitination, and Degradation of MyD88 Adaptor-like (Mal)

by Dunne, Aisling, Carpenter, Susan, Brikos, Constantinos, Gray, Pearl, Strelow, Astrid, Wesche, Holger, Morrice, Nick, O'Neill, Luke A. J.
Published 2010

IRAK1 and IRAK4 promote phosphorylation, ubiquitination, and degradation of MyD88 adaptor-like (Mal).

by Dunne, Aisling, Carpenter, Susan, Brikos, Constantinos, Gray, Pearl, Strelow, Astrid, Wesche, Holger, Morrice, Nick, O'Neill, Luke A. J.
Published in J Biol Chem (2016)

Naturally derived Heme-Oxygenase 1 inducers attenuate inflammatory responses in human dendritic cells and T cells: relevance for psoriasis treatment

by Campbell, Nicole K., Fitzgerald, Hannah K., Malara, Anna, Hambly, Roisin, Sweeney, Cheryl M., Kirby, Brian, Fletcher, Jean M., Dunne, Aisling
Published in Sci Rep (2018)

Trypanosoma brucei Secreted Aromatic Ketoacids Activate the Nrf2/HO-1 Pathway and Suppress Pro-inflammatory Responses in Primary Murine Glia and Macrophages

by Campbell, Nicole K., Williams, David G., Fitzgerald, Hannah K., Barry, Paul J., Cunningham, Clare C., Nolan, Derek P., Dunne, Aisling
Published in Front Immunol (2019)

Arabidopsis AtPARK13, Which Confers Thermotolerance, Targets Misfolded Proteins

by Basak, Indranil, Pal, Ramavati, Patil, Ketan S., Dunne, Aisling, Ho, Hsin-Pin, Lee, Sungsu, Peiris, Diluka, Maple-Grødem, Jodi, Odell, Mark, Chang, Emmanuel J., Larsen, Jan Petter, Møller, Simon G.
Published 2014

Chronic neurodegeneration induces type I interferon synthesis via STING, shaping microglial phenotype and accelerating disease progression

by Nazmi, Arshed, Field, Robert H., Griffin, Eadaoin W., Haugh, Orla, Hennessy, Edel, Cox, Donal, Reis, Renata, Tortorelli, Lucas, Murray, Carol L., Lopez‐Rodriguez, Ana Belen, Jin, Lei, Lavelle, Ed C., Dunne, Aisling, Cunningham, Colm
Published in Glia (2019)

NF-κB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1

by Miggin, Sinead M., Pålsson-McDermott, Eva, Dunne, Aisling, Jefferies, Caroline, Pinteaux, Emmanuel, Banahan, Kathy, Murphy, Caroline, Moynagh, Paul, Yamamoto, Masahiro, Akira, Shizuo, Rothwell, Nancy, Golenbock, Douglas, Fitzgerald, Katherine A., O'Neill, Luke A. J.
Published 2007

TRIL is involved in cytokine production in the brain following Escherichia coli infection

by Wochal, Paulina, Rathinam, Vijay A.K., Dunne, Aisling, Carlson, Thaddeus, Kuang, Wen, Seidl, Kathy J, Hall, J. Perry, Lin, Lih-Ling, Collins, Mary, Schattgen, Stefan A., MacKay, Christopher R., Fagundes, Caio T., Carpenter, Susan, Fitzgerald, Katherine A., O'Neill, Luke A.J.
Published in J Immunol (2014)

Activation of the Nlrp3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

by Masters, Seth L., Dunne, Aisling, Subramanian, Shoba L., Hull, Rebecca L., Tannahill, Gillian M., Sharp, Fiona A., Becker, Christine, Franchi, Luigi, Yoshihara, Eiji, Chen, Zhe, Mullooly, Niamh, Mielke, Lisa A., Harris, James, Coll, Rebecca C., Mills, Kingston H. G., Mok, K. Hun, Newsholme, Philip, Nuñez, Gabriel, Yodoi, Junji, Kahn, Steven E., Lavelle, Ed C., O’Neill, Luke A.J.
Published 2010

A functional variant in TIRAP, also known as MAL, and protection against invasive pneumococcal disease, bacteraemia, malaria and tuberculosis

by Khor, Chiea C., Chapman, Stephen J., Vannberg, Fredrik O, Dunne, Aisling, Murphy, Caroline, Ling, Edmund Y, Frodsham, Angela J., Walley, Andrew J, Kyrieleis, Otto, Khan, Amir, Aucan, Christophe, Segal, Shelley, Moore, Catrin E., Knox, Kyle, Campbell, Sarah J., Lienhardt, Christian, Scott, Anthony, Aaby, Peter, Sow, Oumou Y., Grignani, Robert T., Sillah, Jackson, Sirugo, Girogio, Peshu, Nobert, Williams, Thomas N., Maitland, Kathryn, Davies, Robert J. O., Kwiatkowski, Dominic P., Day, Nicholas P., Yala, Djamel, Crook, Derrick W., Marsh, Kevin, Berkley, James A, O’Neill, Luke A.J., Hill, Adrian V. S.
Published 2007