Benzyl Alcohol: A Novel Treatment for Acetaminophen Overdose?

Por Jaeschke, Hartmut, Du, Kuo
Publicado no Hepatology (2015)

Liuweiwuling tablets protect against acetaminophen hepatotoxicity: What is the protective mechanism?

Por Du, Kuo, Jaeschke, Hartmut
Publicado no World J Gastroenterol (2016)

Mitochondria-Targeted Antioxidant Mito-Tempo Protects against Acetaminophen Hepatotoxicity

Por Du, Kuo, Farhood, Anwar, Jaeschke, Hartmut
Publicado no Arch Toxicol (2016)

Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential

Por Du, Kuo, Ramachandran, Anup, Jaeschke, Hartmut
Publicado no Redox Biol (2016)

BENZYL ALCOHOL PROTECTS AGAINST ACETAMINOPHEN HEPATOTOXICITY BY INHIBITING CYTOCHROME P450 ENZYMES BUT CAUSES MITOCHONDRIAL DYSFUNCTION AND CELL DEATH AT HIGHER DOSES

Por Du, Kuo, McGill, Mitchell R., Xie, Yuchao, Jaeschke, Hartmut
Publicado no Food Chem Toxicol (2015)

PATHOPHYSIOLOGICAL SIGNIFICANCE OF C-JUN N-TERMINAL KINASE IN ACETAMINOPHEN HEPATOTOXICITY

Por Du, Kuo, Xie, Yuchao, McGill, Mitchell R., Jaeschke, Hartmut
Publicado no Expert Opin Drug Metab Toxicol (2015)

Critical Role of FoxO3a in Alcohol-Induced Autophagy and Hepatotoxicity

Por Ni, Hong-Min, Du, Kuo, You, Min, Ding, Wen-Xing
Publicado no Am J Pathol (2013)

Lower Susceptibility of Female Mice to Acetaminophen Hepatotoxicity: Role of Mitochondrial Glutathione, Oxidant Stress and c-Jun N-Terminal Kinase

Por Du, Kuo, Williams, C. David, McGill, Mitchell R., Jaeschke, Hartmut
Publicado no Toxicol Appl Pharmacol (2014)

Critical review of resveratrol in xenobiotic-induced hepatotoxicity

Por McGill, Mitchell R., Du, Kuo, Weemhoff, James L., Jaeschke, Hartmut
Publicado no Food Chem Toxicol (2015)

RESVERATROL PREVENTS PROTEIN NITRATION AND RELEASE OF ENDONUCLEASES FROM MITOCHONDRIA DURING ACETAMINOPHEN HEPATOTOXICITY

Por Du, Kuo, McGill, Mitchell R., Xie, Yuchao, Bajt, Mary Lynn, Jaeschke, Hartmut
Publicado no Food Chem Toxicol (2015)

Editor’s Highlight: Metformin Protects Against Acetaminophen Hepatotoxicity by Attenuation of Mitochondrial Oxidant Stress and Dysfunction

Por Du, Kuo, Ramachandran, Anup, Weemhoff, James L., Chavan, Hemantkumar, Xie, Yuchao, Krishnamurthy, Partha, Jaeschke, Hartmut
Publicado no Toxicol Sci (2016)

The role of the c-Jun N-terminal kinases 1/2 and receptor-interacting protein kinase 3 in furosemide-induced liver injury

Por McGill, Mitchell R., Du, Kuo, Xie, Yuchao, Bajt, Mary Lynn, Ding, Wen-Xing, Jaeschke, Hartmut
Publicado no Xenobiotica (2014)

THE GAP JUNCTION INHIBITOR 2-AMINOETHOXY-DIPHENYL-BORATE PROTECTS AGAINST ACETAMINOPHEN HEPATOTOXICITY BY INHIBITING CYTOCHROME P450 ENZYMES AND C-JUN N-TERMINAL KINASE ACTIVATION

Por Du, Kuo, Williams, C. David, McGill, Mitchell R., Xie, Yuchao, Farhood, Anwar, Vinken, Mathieu, Jaeschke, Hartmut
Publicado em 2013

Differential Susceptibility to Acetaminophen-Induced Liver Injury in Sub-Strains of C57BL/6 Mice: 6N versus 6J

Por Duan, Luqi, Davis, John S., Woolbright, Benjamin L., Du, Kuo, Chakraborty, Mala, Weemhoff, James, Jaeschke, Hartmut, Bourdi, Mohammed
Publicado no Food Chem Toxicol (2016)

Mitochondrial protein adducts formation and mitochondrial dysfunction during N-acetyl-m-aminophenol (AMAP)-induced hepatotoxicity in primary human hepatocytes

Por Xie, Yuchao, McGill, Mitchell R., Du, Kuo, Dorko, Kenneth, Kumer, Sean C., Schmitt, Timothy M., Ding, Wen-Xing, Jaeschke, Hartmut
Publicado no Toxicol Appl Pharmacol (2015)

Removal of Acetaminophen-Protein Adducts by Autophagy Protects Against Acetaminophen-Induced Liver Injury in Mice

Por Ni, Hong-Min, McGill, Mitchell R., Chao, Xiaojuan, Du, Kuo, Williams, Jessica A., Xie, Yuchao, Jaeschke, Hartmut, Ding, Wen-Xing
Publicado no J Hepatol (2016)