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Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential
Acetaminophen (APAP) hepatotoxicity is characterized by an extensive oxidative stress. However, its source, pathophysiological role and possible therapeutic potential if targeted, have been controversially described. Earlier studies argued for cytochrome P450-generated reactive oxygen species (ROS)...
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| Publicat a: | Redox Biol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5065645/ https://ncbi.nlm.nih.gov/pubmed/27744120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.10.001 |
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