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Mechanisms of acetaminophen hepatotoxicity and their translation to the human pathophysiology

Acetaminophen (APAP) overdose is the most common cause of acute liver failure in the United States and mechanisms of liver injury induced by APAP overdose have been the focus of extensive investigation. Studies in the mouse model, which closely reproduces the human condition, have shown that hepatot...

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Podrobná bibliografie
Vydáno v:J Clin Transl Res
Hlavní autoři: Ramachandran, Anup, Jaeschke, Hartmut
Médium: Artigo
Jazyk:Inglês
Vydáno: Whioce Publishing Pte. Ltd. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489132/
https://ncbi.nlm.nih.gov/pubmed/28670625
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