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Mechanisms of acetaminophen hepatotoxicity and their translation to the human pathophysiology

Acetaminophen (APAP) overdose is the most common cause of acute liver failure in the United States and mechanisms of liver injury induced by APAP overdose have been the focus of extensive investigation. Studies in the mouse model, which closely reproduces the human condition, have shown that hepatot...

詳細記述

保存先:
書誌詳細
出版年:J Clin Transl Res
主要な著者: Ramachandran, Anup, Jaeschke, Hartmut
フォーマット: Artigo
言語:Inglês
出版事項: Whioce Publishing Pte. Ltd. 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489132/
https://ncbi.nlm.nih.gov/pubmed/28670625
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