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Mechanisms of acetaminophen hepatotoxicity and their translation to the human pathophysiology

Acetaminophen (APAP) overdose is the most common cause of acute liver failure in the United States and mechanisms of liver injury induced by APAP overdose have been the focus of extensive investigation. Studies in the mouse model, which closely reproduces the human condition, have shown that hepatot...

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書目詳細資料
發表在:J Clin Transl Res
Main Authors: Ramachandran, Anup, Jaeschke, Hartmut
格式: Artigo
語言:Inglês
出版: Whioce Publishing Pte. Ltd. 2017
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489132/
https://ncbi.nlm.nih.gov/pubmed/28670625
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