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Mechanisms of acetaminophen hepatotoxicity and their translation to the human pathophysiology
Acetaminophen (APAP) overdose is the most common cause of acute liver failure in the United States and mechanisms of liver injury induced by APAP overdose have been the focus of extensive investigation. Studies in the mouse model, which closely reproduces the human condition, have shown that hepatot...
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Veröffentlicht in: | J Clin Transl Res |
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Hauptverfasser: | , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
Whioce Publishing Pte. Ltd.
2017
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5489132/ https://ncbi.nlm.nih.gov/pubmed/28670625 |
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