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Mechanisms of acetaminophen hepatotoxicity and their translation to the human pathophysiology

Acetaminophen (APAP) overdose is the most common cause of acute liver failure in the United States and mechanisms of liver injury induced by APAP overdose have been the focus of extensive investigation. Studies in the mouse model, which closely reproduces the human condition, have shown that hepatot...

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Detalhes bibliográficos
Publicado no:J Clin Transl Res
Main Authors: Ramachandran, Anup, Jaeschke, Hartmut
Formato: Artigo
Idioma:Inglês
Publicado em: Whioce Publishing Pte. Ltd. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489132/
https://ncbi.nlm.nih.gov/pubmed/28670625
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