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Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential

Acetaminophen (APAP) hepatotoxicity is characterized by an extensive oxidative stress. However, its source, pathophysiological role and possible therapeutic potential if targeted, have been controversially described. Earlier studies argued for cytochrome P450-generated reactive oxygen species (ROS)...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Redox Biol
Egile Nagusiak: Du, Kuo, Ramachandran, Anup, Jaeschke, Hartmut
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065645/
https://ncbi.nlm.nih.gov/pubmed/27744120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.10.001
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