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Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential
Acetaminophen (APAP) hepatotoxicity is characterized by an extensive oxidative stress. However, its source, pathophysiological role and possible therapeutic potential if targeted, have been controversially described. Earlier studies argued for cytochrome P450-generated reactive oxygen species (ROS)...
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| Publicado no: | Redox Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5065645/ https://ncbi.nlm.nih.gov/pubmed/27744120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.10.001 |
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