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PATHOPHYSIOLOGICAL SIGNIFICANCE OF C-JUN N-TERMINAL KINASE IN ACETAMINOPHEN HEPATOTOXICITY

BACKGROUND: Acetaminophen (APAP) overdose is the leading cause of acute liver failure in the US. Although substantial progress regarding the mechanisms of APAP hepatotoxicity has been made in the past several decades, therapeutic options are still limited and novel treatments are clearly needed. c-j...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Expert Opin Drug Metab Toxicol
Päätekijät: Du, Kuo, Xie, Yuchao, McGill, Mitchell R., Jaeschke, Hartmut
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827771/
https://ncbi.nlm.nih.gov/pubmed/26190663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425255.2015.1071353
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