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PATHOPHYSIOLOGICAL SIGNIFICANCE OF C-JUN N-TERMINAL KINASE IN ACETAMINOPHEN HEPATOTOXICITY

BACKGROUND: Acetaminophen (APAP) overdose is the leading cause of acute liver failure in the US. Although substantial progress regarding the mechanisms of APAP hepatotoxicity has been made in the past several decades, therapeutic options are still limited and novel treatments are clearly needed. c-j...

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Foilsithe in:Expert Opin Drug Metab Toxicol
Main Authors: Du, Kuo, Xie, Yuchao, McGill, Mitchell R., Jaeschke, Hartmut
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827771/
https://ncbi.nlm.nih.gov/pubmed/26190663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425255.2015.1071353
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