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PATHOPHYSIOLOGICAL SIGNIFICANCE OF C-JUN N-TERMINAL KINASE IN ACETAMINOPHEN HEPATOTOXICITY

BACKGROUND: Acetaminophen (APAP) overdose is the leading cause of acute liver failure in the US. Although substantial progress regarding the mechanisms of APAP hepatotoxicity has been made in the past several decades, therapeutic options are still limited and novel treatments are clearly needed. c-j...

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Bibliografiska uppgifter
I publikationen:Expert Opin Drug Metab Toxicol
Huvudupphovsmän: Du, Kuo, Xie, Yuchao, McGill, Mitchell R., Jaeschke, Hartmut
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827771/
https://ncbi.nlm.nih.gov/pubmed/26190663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425255.2015.1071353
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