The role of the c-Jun N-terminal kinases 1/2 and receptor-interacting protein kinase 3 in furosemide-induced liver injury

1. The mechanisms of furosemide (FS) hepatotoxicity were explored in mice. Specifically, C57Bl/6J mice were treated with 500 mg FS / kg bodyweight and c-Jun N-terminal kinase (JNK) activation and RIP3 expression were measured by western blotting. Co-treatment with furosemide and the JNK inhibitor SP...

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Vydáno v:Xenobiotica
Hlavní autoři: McGill, Mitchell R., Du, Kuo, Xie, Yuchao, Bajt, Mary Lynn, Ding, Wen-Xing, Jaeschke, Hartmut
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442771/
https://ncbi.nlm.nih.gov/pubmed/25423287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/00498254.2014.986250
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