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The role of the c-Jun N-terminal kinases 1/2 and receptor-interacting protein kinase 3 in furosemide-induced liver injury
1. The mechanisms of furosemide (FS) hepatotoxicity were explored in mice. Specifically, C57Bl/6J mice were treated with 500 mg FS / kg bodyweight and c-Jun N-terminal kinase (JNK) activation and RIP3 expression were measured by western blotting. Co-treatment with furosemide and the JNK inhibitor SP...
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| Publicat a: | Xenobiotica |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4442771/ https://ncbi.nlm.nih.gov/pubmed/25423287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/00498254.2014.986250 |
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