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Chlorpromazine protects against acetaminophen-induced liver injury in mice by modulating autophagy and c-Jun N-terminal kinase activation

BACKGROUND AND AIM: Overdose of acetaminophen (APAP) leads to liver injury, which is one of the most common causes of liver failure in the United States. We previously demonstrated that pharmacological activation of autophagy protects against APAP-induced liver injury in mice via removal of damaged...

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Detalhes bibliográficos
Publicado no:Liver Res
Main Authors: Li, Yuan, Ni, Hong-Min, Jaeschke, Hartmut, Ding, Wen-Xing
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6897503/
https://ncbi.nlm.nih.gov/pubmed/31815033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.livres.2019.01.004
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