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Differential Susceptibility to Acetaminophen-Induced Liver Injury in Sub-Strains of C57BL/6 Mice: 6N versus 6J

Mouse models of acetaminophen (APAP) hepatotoxicity are considered relevant for the human pathophysiology. The C57BL/6 strain is most popular because it is the background strain of gene knock-out mice. However, conflicting results in the literature may have been caused by sub-strain mismatches, e.g....

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Detalhes bibliográficos
Publicado no:Food Chem Toxicol
Main Authors: Duan, Luqi, Davis, John S., Woolbright, Benjamin L., Du, Kuo, Chakraborty, Mala, Weemhoff, James, Jaeschke, Hartmut, Bourdi, Mohammed
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123947/
https://ncbi.nlm.nih.gov/pubmed/27773698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fct.2016.10.021
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