Ubiquitin-Specific Proteases as Druggable Targets

Por Davis, Mindy I., Simeonov, Anton
Publicado no Drug Target Rev (2015)

Method for Assaying the Lipid Kinase Phosphatidylinositol-5-phosphate 4-kinase α in Quantitative High-Throughput Screening (qHTS) Bioluminescent Format

Por Davis, Mindy I., Sasaki, Atsuo T., Simeonov, Anton
Publicado no Methods Mol Biol (2016)

Bioluminescence Methods for Assaying Kinases in Quantitative High-Throughput Screening (qHTS) Format Applied to Yes1 Tyrosine Kinase, Glucokinase and PI5P4Kα Lipid Kinase

Por Davis, Mindy I., Auld, Douglas S., Inglese, James
Publicado no Methods Mol Biol (2016)

Avoiding Fluorescence Assay Interference—The Case for Diaphorase

Por Hall, Matthew D., Simeonov, Anton, Davis, Mindy I.
Publicado no Assay Drug Dev Technol (2016)

Diaphorase Coupling Protocols for Red-Shifting Dehydrogenase Assays

Por Davis, Mindy I., Shen, Min, Simeonov, Anton, Hall, Matthew D.
Publicado no Assay Drug Dev Technol (2016)

Crystal structure of prostate-specific membrane antigen, a tumor marker and peptidase

Por Davis, Mindy I., Bennett, Melanie J., Thomas, Leonard M., Bjorkman, Pamela J.
Publicado em 2005

Spectroscopic and Electronic Structure Study of the Enzyme-Substrate Complex of Intradiol Dioxygenases: Substrate Activation by a High Spin Ferric Non-Heme Iron Site

Por Pau, Monita Y. M., Davis, Mindy I., Orville, Allen M., Lipscomb, John D., Solomon, Edward I.
Publicado em 2007

Identification of potent Yes1 kinase inhibitors using a library screening approach

Por Patel, Paresma R., Sun, Hongmao, Li, Samuel Q., Shen, Min, Khan, Javed, Thomas, Craig J., Davis, Mindy I.
Publicado em 2013

A Panel of Diverse Assays to Interrogate the Interaction between Glucokinase and Glucokinase Regulatory Protein, Two Vital Proteins in Human Disease

Por Rees, Matthew G., Davis, Mindy I., Shen, Min, Titus, Steve, Raimondo, Anne, Barrett, Amy, Gloyn, Anna L., Collins, Francis S., Simeonov, Anton
Publicado em 2014

Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery

Por Merk, Alan, Bartesaghi, Alberto, Banerjee, Soojay, Falconieri, Veronica, Rao, Prashant, Davis, Mindy, Pragani, Rajan, Boxer, Matthew, Earl, Lesley A., Milne, Jacqueline L.S., Subramaniam, Sriram
Publicado no Cell (2016)

CS-33 DISCOVERY OF A p53-INDEPENDENT SUPPRESSOR OF SENESCENCE OF GLIOBLASTOMA MULTIFORME

Por Sumita, Kazutaka, Davis, Mindy, Pragani, Rajan, Terakawa, Jumpei, Daikoku, Takiko, Majd, Nazanin, Shen, Min, Li, Zhuyin, Hu, Xin, Cantley, Lewis, Boxer, Matthew, Simeonov, Anton, Sasaki, Atsuo
Publicado em 2014

A Homogeneous, High-Throughput Assay for Phosphatidylinositol 5-Phosphate 4-Kinase with a Novel, Rapid Substrate Preparation

Por Davis, Mindy I., Sasaki, Atsuo T., Shen, Min, Emerling, Brooke M., Thorne, Natasha, Michael, Sam, Pragani, Rajan, Boxer, Matthew, Sumita, Kazutaka, Takeuchi, Koh, Auld, Douglas S., Li, Zhuyin, Cantley, Lewis C., Simeonov, Anton
Publicado em 2013

Inheritance of rare functional GCKR variants and their contribution to triglyceride levels in families

Por Rees, Matthew G., Raimondo, Anne, Wang, Jian, Ban, Matthew R., Davis, Mindy I., Barrett, Amy, Ranft, Jessica, Jagdhuhn, David, Waterstradt, Rica, Baltrusch, Simone, Simeonov, Anton, Collins, Francis S., Hegele, Robert A., Gloyn, Anna L.
Publicado em 2014

Biochemical, Cellular, and Biophysical Characterization of a Potent Inhibitor of Mutant Isocitrate Dehydrogenase IDH1

Por Davis, Mindy I., Gross, Stefan, Shen, Min, Straley, Kimberly S., Pragani, Rajan, Lea, Wendy A., Popovici-Muller, Janeta, DeLaBarre, Byron, Artin, Erin, Thorne, Natasha, Auld, Douglas S., Li, Zhuyin, Dang, Lenny, Boxer, Matthew B., Simeonov, Anton
Publicado em 2014

mQC: A Heuristic Quality-Control Metric for High-Throughput Drug Combination Screening

Por Chen, Lu, Wilson, Kelli, Goldlust, Ian, Mott, Bryan T., Eastman, Richard, Davis, Mindy I., Zhang, Xiaohu, McKnight, Crystal, Klumpp-Thomas, Carleen, Shinn, Paul, Simmons, John, Gormally, Mike, Michael, Sam, Thomas, Craig J., Ferrer, Marc, Guha, Rajarshi
Publicado no Sci Rep (2016)

Identification of Novel Plasmodium falciparum Hexokinase Inhibitors with Antiparasitic Activity

Por Davis, Mindy I., Patrick, Stephen L., Blanding, Walker M., Dwivedi, Varun, Suryadi, Jimmy, Golden, Jennifer E., Coussens, Nathan P., Lee, Olivia W., Shen, Min, Boxer, Matthew B., Hall, Matthew D., Sharlow, Elizabeth R., Drew, Mark E., Morris, James C.
Publicado no Antimicrob Agents Chemother (2016)

Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Mod...

Por Davis, Mindy I., Pragani, Rajan, Fox, Jennifer T., Shen, Min, Parmar, Kalindi, Gaudiano, Emily F., Liu, Li, Tanega, Cordelle, McGee, Lauren, Hall, Matthew D., McKnight, Crystal, Shinn, Paul, Nelson, Henrike, Chattopadhyay, Debasish, D'Andrea, Alan D., Auld, Douglas S., DeLucas, Larry J., Li, Zhuyin, Boxer, Matthew B., Simeonov, Anton
Publicado no J Biol Chem (2016)

Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays

Por Urban, Daniel J., Martinez, Natalia J., Davis, Mindy I., Brimacombe, Kyle R., Cheff, Dorian M., Lee, Tobie D., Henderson, Mark J., Titus, Steven A., Pragani, Rajan, Rohde, Jason M., Liu, Li, Fang, Yuhong, Karavadhi, Surendra, Shah, Pranav, Lee, Olivia W., Wang, Amy, McIver, Andrew, Zheng, Hongchao, Wang, Xiaodong, Xu, Xin, Jadhav, Ajit, Simeonov, Anton, Shen, Min, Boxer, Matthew B., Hall, Matthew D.
Publicado no Sci Rep (2017)