Identification of Novel Plasmodium falciparum Hexokinase Inhibitors with Antiparasitic Activity

Plasmodium falciparum, the deadliest species of malaria parasites, is dependent on glycolysis for the generation of ATP during the pathogenic red blood cell stage. Hexokinase (HK) catalyzes the first step in glycolysis, transferring the γ-phosphoryl group of ATP to glucose to yield glucose-6-phospha...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Davis, Mindy I., Patrick, Stephen L., Blanding, Walker M., Dwivedi, Varun, Suryadi, Jimmy, Golden, Jennifer E., Coussens, Nathan P., Lee, Olivia W., Shen, Min, Boxer, Matthew B., Hall, Matthew D., Sharlow, Elizabeth R., Drew, Mark E., Morris, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038330/
https://ncbi.nlm.nih.gov/pubmed/27458230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00914-16
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados