Interrogating a Hexokinase-Selected Small-Molecule Library for Inhibitors of Plasmodium falciparum Hexokinase

Parasites in the genus Plasmodium cause disease throughout the tropic and subtropical regions of the world. P. falciparum, one of the deadliest species of the parasite, relies on glycolysis for the generation of ATP while it inhabits the mammalian red blood cell. The first step in glycolysis is cata...

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Detalhes bibliográficos
Main Authors: Harris, Michael T., Walker, Dawn M., Drew, Mark E., Mitchell, William G., Dao, Kevin, Schroeder, Chad E., Flaherty, Daniel P., Weiner, Warren S., Golden, Jennifer E., Morris, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719756/
https://ncbi.nlm.nih.gov/pubmed/23716053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00662-13
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