Optimization and Evaluation of Antiparasitic Benzamidobenzoic Acids as Inhibitors of a Kinetoplastid Hexokinase 1

Kinetoplastid-based infections are neglected diseases that represent a significant human health issue. Chemotherapeutic options are limited due to toxicity, parasite susceptibility, and poor patient compliance. In response, we studied a molecular target-directed approach involving intervention of he...

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Publicado no:ChemMedChem
Main Authors: Flaherty, Daniel P., Harris, Michael T., Schroeder, Chad E., Khan, Haaris, Kahney, Elizabeth W., Hackler, Amber L., Patrick, Stephen L., Weiner, Warren S., Aubé, Jeffrey, Sharlow, Elizabeth R., Morris, James C., Golden, Jennifer E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808564/
https://ncbi.nlm.nih.gov/pubmed/29105342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201700592
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