Biochemical and Antiparasitic Properties of Inhibitors of the Plasmodium falciparum Calcium-Dependent Protein Kinase PfCDPK1

PfCDPK1 is a Plasmodium falciparum calcium-dependent protein kinase, which has been identified as a potential target for novel antimalarial chemotherapeutics. In order to further investigate the role of PfCDPK1, we established a high-throughput in vitro biochemical assay and used it to screen a libr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ansell, Keith H., Jones, Hayley M., Whalley, David, Hearn, Alisdair, Taylor, Debra L., Patin, Emmanuel C., Chapman, Timothy M., Osborne, Simon A., Wallace, Claire, Birchall, Kristian, Large, Jonathan, Bouloc, Nathalie, Smiljanic-Hurley, Ela, Clough, Barbara, Moon, Robert W., Green, Judith L., Holder, Anthony A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187893/
https://ncbi.nlm.nih.gov/pubmed/25070106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02959-14
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados