Beyond the unwinding: role of TOP1MT in mitochondrial translation

بواسطة Baechler, Simone A, Dalla Rosa, Ilaria, Spinazzola, Antonella, Pommier, Yves
الحاوية / القاعدة Cell Cycle (2019)

Transcription profiling suggests that mitochondrial topoisomerase IB acts as a topological barrier and regulator of mitochondrial DNA transcription

بواسطة Dalla Rosa, Ilaria, Zhang, Hongliang, Khiati, Salim, Wu, Xiaolin, Pommier, Yves
الحاوية / القاعدة J Biol Chem (2017)

Coordinated regulation of mitochondrial topoisomerase IB with mitochondrial nuclear encoded genes and MYC

بواسطة Zoppoli, Gabriele, Douarre, Céline, Dalla Rosa, Ilaria, Liu, Hongfang, Reinhold, William, Pommier, Yves
منشور في 2011

Increased negative supercoiling of mtDNA in TOP1mt knockout mice and presence of topoisomerases IIα and IIβ in vertebrate mitochondria

بواسطة Zhang, Hongliang, Zhang, Yong-Wei, Yasukawa, Takehiro, Dalla Rosa, Ilaria, Khiati, Salim, Pommier, Yves
منشور في 2014

Mapping Topoisomerase Sites in Mitochondrial DNA with a Poisonous Mitochondrial Topoisomerase I (Top1mt)

بواسطة Dalla Rosa, Ilaria, Huang, Shar-yin N., Agama, Keli, Khiati, Salim, Zhang, Hongliang, Pommier, Yves
منشور في 2014

TDP1 repairs nuclear and mitochondrial DNA damage induced by chain-terminating anticancer and antiviral nucleoside analogs

بواسطة Huang, Shar-yin N., Murai, Junko, Dalla Rosa, Ilaria, Dexheimer, Thomas S., Naumova, Alena, Gmeiner, William H., Pommier, Yves
منشور في 2013

Mitochondrial Topoisomerase I is Critical for Mitochondrial Integrity and Cellular Energy Metabolism

بواسطة Douarre, Céline, Sourbier, Carole, Dalla Rosa, Ilaria, Brata Das, Benu, Redon, Christophe E., Zhang, Hongliang, Neckers, Len, Pommier, Yves
منشور في 2012

Mitochondrial topoisomerase I (Top1mt) is a novel limiting factor of doxorubicin cardiotoxicity

بواسطة Khiati, Salim, Dalla Rosa, Ilaria, Sourbier, Carole, Ma, Xuefei, Rao, V. Ashutosh, Neckers, Leonard M, Zhang, Hongliang, Pommier, Yves
منشور في 2014

Lack of mitochondrial topoisomerase I (TOP1mt) impairs liver regeneration

بواسطة Khiati, Salim, Baechler, Simone A., Factor, Valentina M., Zhang, Hongliang, Huang, Shar-yin N., Dalla Rosa, Ilaria, Sourbier, Carole, Neckers, Leonard, Thorgeirsson, Snorri S., Pommier, Yves
الحاوية / القاعدة Proc Natl Acad Sci U S A (2015)

Negative regulation of mitochondrial transcription by mitochondrial topoisomerase I

بواسطة Sobek, Stefan, Dalla Rosa, Ilaria, Pommier, Yves, Bornholz, Beatrice, Kalfalah, Faiza, Zhang, Hongliang, Wiesner, Rudolf J., von Kleist-Retzow, Jürgen-Christoph, Hillebrand, Frank, Schaal, Heiner, Mielke, Christian, Christensen, Morten O., Boege, Fritz
منشور في 2013

LETM1 couples mitochondrial DNA metabolism and nutrient preference

بواسطة Durigon, Romina, Mitchell, Alice L, Jones, Aleck WE, Manole, Andreea, Mennuni, Mara, Hirst, Elizabeth MA, Houlden, Henry, Maragni, Giuseppe, Lattante, Serena, Doronzio, Paolo Niccolo’, Dalla Rosa, Ilaria, Zollino, Marcella, Holt, Ian J, Spinazzola, Antonella
الحاوية / القاعدة EMBO Mol Med (2018)

MPV17L2 is required for ribosome assembly in mitochondria

بواسطة Dalla Rosa, Ilaria, Durigon, Romina, Pearce, Sarah F., Rorbach, Joanna, Hirst, Elizabeth M.A., Vidoni, Sara, Reyes, Aurelio, Brea-Calvo, Gloria, Minczuk, Michal, Woellhaf, Michael W., Herrmann, Johannes M., Huynen, Martijn A., Holt, Ian J., Spinazzola, Antonella
منشور في 2014

Pathological ribonuclease H1 causes R-loop depletion and aberrant DNA segregation in mitochondria

بواسطة Akman, Gokhan, Desai, Radha, Bailey, Laura J., Yasukawa, Takehiro, Dalla Rosa, Ilaria, Durigon, Romina, Holmes, J. Bradley, Moss, Chloe F., Mennuni, Mara, Houlden, Henry, Crouch, Robert J., Hanna, Michael G., Pitceathly, Robert D. S., Spinazzola, Antonella, Holt, Ian J.
الحاوية / القاعدة Proc Natl Acad Sci U S A (2016)

Aberrant ribonucleotide incorporation and multiple deletions in mitochondrial DNA of the murine MPV17 disease model

بواسطة Moss, Chloe F., Dalla Rosa, Ilaria, Hunt, Lilian E., Yasukawa, Takehiro, Young, Robert, Jones, Aleck W. E., Reddy, Kaalak, Desai, Radha, Virtue, Sam, Elgar, Greg, Voshol, Peter, Taylor, Martin S., Holt, Ian J., Reijns, Martin A. M., Spinazzola, Antonella
الحاوية / القاعدة Nucleic Acids Res (2017)

Mitochondrial tyrosyl‐DNA phosphodiesterase 2 and its TDP2(S) short isoform

بواسطة Huang, Shar‐yin N, Dalla Rosa, Ilaria, Michaels, Stephanie A, Tulumello, David V, Agama, Keli, Khiati, Salim, Jean, Sae Rin, Baechler, Simone A, Factor, Valentina M, Varma, Sudhir, Murai, Junko, Miller Jenkins, Lisa M, Kelley, Shana O, Pommier, Yves
الحاوية / القاعدة EMBO Rep (2018)

Identification of a novel heterozygous guanosine monophosphate reductase (GMPR) variant in a patient with a late‐onset disorder of mitochondrial DNA maintenance

بواسطة Sommerville, Ewen W., Dalla Rosa, Ilaria, Rosenberg, Masha M., Bruni, Francesco, Thompson, Kyle, Rocha, Mariana, Blakely, Emma L., He, Langping, Falkous, Gavin, Schaefer, Andrew M., Yu‐Wai‐Man, Patrick, Chinnery, Patrick F., Hedstrom, Lizbeth, Spinazzola, Antonella, Taylor, Robert W., Gorman, Gráinne S.
الحاوية / القاعدة Clin Genet (2019)

MPV17 Loss Causes Deoxynucleotide Insufficiency and Slow DNA Replication in Mitochondria

بواسطة Dalla Rosa, Ilaria, Cámara, Yolanda, Durigon, Romina, Moss, Chloe F., Vidoni, Sara, Akman, Gokhan, Hunt, Lilian, Johnson, Mark A., Grocott, Sarah, Wang, Liya, Thorburn, David R., Hirano, Michio, Poulton, Joanna, Taylor, Robert W., Elgar, Greg, Martí, Ramon, Voshol, Peter, Holt, Ian J., Spinazzola, Antonella
الحاوية / القاعدة PLoS Genet (2016)

ATAD3 gene cluster deletions cause cerebellar dysfunction associated with altered mitochondrial DNA and cholesterol metabolism

بواسطة Desai, Radha, Frazier, Ann E., Durigon, Romina, Patel, Harshil, Jones, Aleck W., Dalla Rosa, Ilaria, Lake, Nicole J., Compton, Alison G., Mountford, Hayley S., Tucker, Elena J., Mitchell, Alice L. R., Jackson, Deborah, Sesay, Abdul, Di Re, Miriam, van den Heuvel, Lambert P., Burke, Derek, Francis, David, Lunke, Sebastian, McGillivray, George, Mandelstam, Simone, Mochel, Fanny, Keren, Boris, Jardel, Claude, Turner, Anne M., Ian Andrews, P., Smeitink, Jan, Spelbrink, Johannes N., Heales, Simon J., Kohda, Masakazu, Ohtake, Akira, Murayama, Kei, Okazaki, Yasushi, Lombès, Anne, Holt, Ian J., Thorburn, David R., Spinazzola, Antonella
الحاوية / القاعدة Brain (2017)