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Mitochondrial Topoisomerase I is Critical for Mitochondrial Integrity and Cellular Energy Metabolism
BACKGROUND: Mitochondria contain their own DNA genome (mtDNA), as well as specific DNA replication and protein synthesis machineries. Relaxation of the circular, double-stranded mtDNA relies on the presence of topoisomerase activity. Three different topoisomerases have been identified in mitochondri...
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| Hoofdauteurs: | , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401127/ https://ncbi.nlm.nih.gov/pubmed/22911747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041094 |
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