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Coordinated regulation of mitochondrial topoisomerase IB with mitochondrial nuclear encoded genes and MYC
Mitochondrial DNA (mtDNA) is entirely dependent on nuclear genes for its transcription and replication. One of these genes is TOP1MT, which encodes the mitochondrial DNA topoisomerase IB, involved in mtDNA relaxation. To elucidate TOP1MT regulation, we performed genome-wide profiling across the 60-c...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3159436/ https://ncbi.nlm.nih.gov/pubmed/21531700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr208 |
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