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Mapping Topoisomerase Sites in Mitochondrial DNA with a Poisonous Mitochondrial Topoisomerase I (Top1mt)

Mitochondrial topoisomerase I (Top1mt) is a type IB topoisomerase present in vertebrates and exclusively targeted to mitochondria. Top1mt relaxes mitochondrial DNA (mtDNA) supercoiling by introducing transient cleavage complexes wherein the broken DNA strand swivels around the intact strand. Top1mt...

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Detaylı Bibliyografya
Asıl Yazarlar: Dalla Rosa, Ilaria, Huang, Shar-yin N., Agama, Keli, Khiati, Salim, Zhang, Hongliang, Pommier, Yves
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140277/
https://ncbi.nlm.nih.gov/pubmed/24798329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.555367
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