Combination of HDAC and topoisomerase inhibitors in small cell lung cancer

بواسطة Gray, Jhanelle, Cubitt, Christopher L., Zhang, Shumin, Chiappori, Alberto
منشور في 2012

Inhibition of CRM1-dependent nuclear export sensitizes malignant cells to cytotoxic and targeted agents

بواسطة Turner, Joel G., Dawson, Jana, Cubitt, Christopher L., Baz, Rachid, Sullivan, Daniel M.
منشور في 2014

Small molecule inhibition of lysine-specific demethylase 1 (LSD1) and histone deacetylase (HDAC) alone and in combination in Ewing sarcoma cell lines

بواسطة Welch, Darcy, Kahen, Elliot, Fridley, Brooke, Brohl, Andrew S., Cubitt, Christopher L., Reed, Damon R.
الحاوية / القاعدة PLoS One (2019)

MK-2206, an Akt inhibitor, enhances carboplatinum/paclitaxel efficacy in gastric cancer cell lines

بواسطة Almhanna, Khaldoun, Cubitt, Christopher L, Zhang, Shumin, Kazim, Sabiha, Husain, Kazim, Sullivan, Dan, Sebti, Said, Malafa, Mokenge
منشور في 2013

Identification of clinically achievable combination therapies in childhood rhabdomyosarcoma

بواسطة Kahen, Elliot, Yu, Diana, Harrison, Douglas J., Clark, Justine, Hingorani, Pooja, Cubitt, Christopher L., Reed, Damon R.
الحاوية / القاعدة Cancer Chemother Pharmacol (2016)

CRM1 Inhibition Sensitizes Drug Resistant Human Myeloma Cells to Topoisomerase II and Proteasome Inhibitors both In Vitro and Ex Vivo

بواسطة Turner, Joel G., Dawson, Jana, Emmons, Michael F., Cubitt, Christopher L., Kauffman, Michael, Shacham, Sharon, Hazlehurst, Lori A., Sullivan, Daniel M.
منشور في 2013

Identification of Synergistic, Clinically Achievable, Combination Therapies for Osteosarcoma

بواسطة Yu, Diana, Kahen, Elliot, Cubitt, Christopher L., McGuire, Jeremy, Kreahling, Jenny, Lee, Jae, Altiok, Soner, Lynch, Conor C., Sullivan, Daniel M., Reed, Damon R.
الحاوية / القاعدة Sci Rep (2015)

Inhibition of ER stress–associated IRE-1/XBP-1 pathway reduces leukemic cell survival

بواسطة Tang, Chih-Hang Anthony, Ranatunga, Sujeewa, Kriss, Crystina L., Cubitt, Christopher L., Tao, Jianguo, Pinilla-Ibarz, Javier A., Del Valle, Juan R., Hu, Chih-Chi Andrew
منشور في 2014

Melphalan and exportin 1 inhibitors exert synergistic anti-tumor effects in preclinical models of human multiple myeloma

بواسطة Turner, Joel G., Cui, Yan, Bauer, Alexis A., Dawson, Jana L., Gomez, Juan A., Kim, Jongphil, Cubitt, Christopher L., Nishihori, Taiga, Dalton, William S., Sullivan, Daniel M.
الحاوية / القاعدة Cancer Res (2020)

Rapid Screening of Novel Agents for Combination Therapy in Sarcomas

بواسطة Cubitt, Christopher L., Menth, Jiliana, Dawson, Jana, Martinez, Gary V., Foroutan, Parastou, Morse, David L., Bui, Marilyn M., Letson, G. Douglas, Sullivan, Daniel M., Reed, Damon R.
منشور في 2013

Phase I pharmacokinetic and pharmacodynamic study of triciribine phosphate monohydrate, a small-molecule inhibitor of AKT phosphorylation, in adult subjects with solid tumors conta...

بواسطة Garrett, Christopher R., Coppola, Domenico, Wenham, Robert M., Cubitt, Christopher L., Neuger, Anthony M., Frost, Timothy J., Lush, Richard M., Sullivan, Daniel M., Cheng, Jin Q., Sebti, Saïd M.
الحاوية / القاعدة Invest New Drugs (2010)

Targeting Aurora kinase A and JAK2 prevents GVHD while maintaining T(reg) and antitumor CTL function

بواسطة Betts, Brian C., Veerapathran, Anandharaman, Pidala, Joseph, Yang, Hua, Horna, Pedro, Walton, Kelly, Cubitt, Christopher L., Gunawan, Steven, Lawrence, Harshani R., Lawrence, Nicholas J., Sebti, Said M., Anasetti, Claudio
الحاوية / القاعدة Sci Transl Med (2017)

Neurofibromin level directs RAS pathway signaling and mediates sensitivity to targeted agents in malignant peripheral nerve sheath tumors

بواسطة Kahen, Elliot John, Brohl, Andrew, Yu, Diana, Welch, Darcy, Cubitt, Christopher L., Lee, Jae K., Chen, Yunyun, Yoder, Sean J., Teer, Jamie K., Zhang, Yonghong O., Wallace, Margaret R., Reed, Damon R.
الحاوية / القاعدة Oncotarget (2018)

Phase I Clinical Trial of Selinexor in Combination with Daunorubicin and Cytarabine in Previously Untreated Poor-Risk Acute Myeloid Leukemia

بواسطة Sweet, Kendra, Komrokji, Rami, Padron, Eric, Cubitt, Christopher L., Turner, Joel G., Zhou, Junmin, List, Alan F., Sallman, David A., Dawson, Jana L., Sullivan, Daniel M., Chavez, Julio, Shah, Bijal D., Lancet, Jeffrey E.
الحاوية / القاعدة Clin Cancer Res (2019)

Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases

بواسطة Schonbrunn, Ernst, Betzi, Stephane, Alam, Riazul, Martin, Mathew P., Becker, Andreas, Han, Huijong, Francis, Rawle, Chakrasali, Ramappa, Jakkaraj, Sudhakar, Kazi, Aslamuzzaman, Sebti, Said M., Cubitt, Christopher L., Gebhard, Anthony W., Hazlehurst, Lori A., Tash, Joseph S., Georg, Gunda I.
منشور في 2013

A novel c-Met inhibitor, MK8033, synergizes with carboplatin plus paclitaxel to inhibit ovarian cancer cell growth

بواسطة MARCHION, DOUGLAS C., BICAKU, ELONA, XIONG, YIN, ZGHEIB, NADIM BOU, SAWAH, ENTIDHAR AL, STICKLES, XIAOMANG BA, JUDSON, PATRICIA L., LOPEZ, ALEX S., CUBITT, CHRISTOPHER L., GONZALEZ-BOSQUET, JESUS, WENHAM, ROBERT M., APTE, SACHIN M., BERGLUND, ANDERS, LANCASTER, JOHNATHAN M.
الحاوية / القاعدة Oncol Rep (2013)

The O-glycan pathway is associated with in vitro sensitivity to gemcitabine and overall survival from ovarian cancer

بواسطة ZGHEIB, NADIM BOU, XIONG, YIN, MARCHION, DOUGLAS C., BICAKU, ELONA, CHON, HYE SOOK, STICKLES, XIAOMANG BA, AL SAWAH, ENTIDHAR, JUDSON, PATRICIA L., HAKAM, ARDESHIR, GONZALEZ-BOSQUET, JESUS, WENHAM, ROBERT M., APTE, SACHIN M., CUBITT, CHRISTOPHER L., CHEN, DUNG TSA, LANCASTER, JOHNATHAN M.
منشور في 2012

Sensitivity of ovarian cancer cells to acetaminophen reveals biological pathways that affect patient survival

بواسطة BUSH, STEPHEN H., TOLLIN, SHARON, MARCHION, DOUGLAS C., XIONG, YIN, ABBASI, FOROUGH, RAMIREZ, INGRID J., ZGHEIB, NADIM BOU, BOAC, BERNADETTE, JUDSON, PATRICIA L., CHON, HYE SOOK, WENHAM, ROBERT M., APTE, SACHIN M., CUBITT, CHRISTOPHER L., BERGLUND, ANDERS E., HAVRILESKY, LAURA J., LANCASTER, JOHNATHAN M.
الحاوية / القاعدة Mol Clin Oncol (2016)