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Combination of HDAC and topoisomerase inhibitors in small cell lung cancer
Histone deacetylase (HDAC) inhibitors, including MGCD0103 and vorinostat, have led to tumor growth inhibition and apoptosis in vivo. However, with limited single-agent activity demonstrated in solid tumor trials, we examined the potential for enhanced effects in combination with topoisomerase I and...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3408970/ https://ncbi.nlm.nih.gov/pubmed/22441819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.19848 |
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