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Phase I/II Study of the Src Inhibitor Dasatinib in Combination With Erlotinib in Advanced Non–Small-Cell Lung Cancer

PURPOSE: Src family kinase (SFK) proteins are frequently activated in cancer and can coordinate tumor cell growth, survival, invasion, and angiogenesis. Given the importance of SFK signaling in cancer, known cooperation between SFK and epidermal growth factor receptor (EGFR) signaling, and efficacy...

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Autors principals: Haura, Eric B., Tanvetyanon, Tawee, Chiappori, Alberto, Williams, Charles, Simon, George, Antonia, Scott, Gray, Jhanelle, Litschauer, Sharon, Tetteh, Leticia, Neuger, Anthony, Song, Lanxi, Rawal, Bhupendra, Schell, Michael J., Bepler, Gerold
Format: Artigo
Idioma:Inglês
Publicat: American Society of Clinical Oncology 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040065/
https://ncbi.nlm.nih.gov/pubmed/20142592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.25.4029
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