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Phase I/II Study of the Src Inhibitor Dasatinib in Combination With Erlotinib in Advanced Non–Small-Cell Lung Cancer

PURPOSE: Src family kinase (SFK) proteins are frequently activated in cancer and can coordinate tumor cell growth, survival, invasion, and angiogenesis. Given the importance of SFK signaling in cancer, known cooperation between SFK and epidermal growth factor receptor (EGFR) signaling, and efficacy...

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書誌詳細
主要な著者: Haura, Eric B., Tanvetyanon, Tawee, Chiappori, Alberto, Williams, Charles, Simon, George, Antonia, Scott, Gray, Jhanelle, Litschauer, Sharon, Tetteh, Leticia, Neuger, Anthony, Song, Lanxi, Rawal, Bhupendra, Schell, Michael J., Bepler, Gerold
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Clinical Oncology 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040065/
https://ncbi.nlm.nih.gov/pubmed/20142592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.25.4029
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