Construction of functionalized tricyclic dihydropyrazino-quinazolinedione chemotypes via an Ugi/N-acyliminium ion cyclization cascade

Por Gunawan, Steven, Hulme, Christopher
Publicado em 2013

Bifunctional building blocks in the Ugi-azide condensation reaction: A general strategy toward exploration of new molecular diversity

Por Gunawan, Steven, Hulme, Christopher
Publicado em 2013

Concise One-Pot Preparation of Unique Bis-Pyrrolidinone Tetrazoles

Por Gunawan, Steven, Petit, Joachim, Hulme, Christopher
Publicado em 2012

Concise route to a series of novel 3-(tetrazol-5-yl)quinoxalin-2(1H)-ones

Por Gunawan, Steven, Nichol, Gary, Hulme, Christopher
Publicado em 2012

2-Butyl-11-phenyl-5,10-dihydro-1H-benzo[e]imidazo[1,5-a][1,4]diazepine-1,3(2H)-dione

Por Nichol, Gary S., Gunawan, Steven, Dietrich, Justin, Hulme, Christopher
Publicado em 2010

Concise Preparation of Novel Tricyclic Chemotypes: Fused Hydantoin-benzodiazepines

Por Gunawan, Steven, Nichol, Gary S., Chappeta, Shashi, Dietrich, Justin, Hulme, Christopher
Publicado em 2010

2-Propyl 3,3-dibromo-2-hydroxy­pyrrolidine-1-carboxyl­ate

Por Nichol, Gary S., Gunawan, Steven, Xu, Zhigang, Dietrich, Justin, Hulme, Christopher
Publicado em 2010

Synthesis of Tetrazolo-Fused Benzodiazepines and Benzodiazepinones by a Two-Step Protocol Using an Ugi-Azide Reaction for Initial Diversity Generation

Por Gunawan, Steven, Ayaz, Muhammad, De Moliner, Fabio, Frett, Brendan, Kaiser, Christine, Patrick, Nina, Xu, Zhigang, Hulme, Christopher
Publicado em 2012

Potent dual BET bromodomain-kinase inhibitors as value added multi-targeted chemical probes and cancer therapeutics

Por Ember, Stuart W., Lambert, Que T., Berndt, Norbert, Gunawan, Steven, Ayaz, Muhammad, Tauro, Marilena, Zhu, Jin-Yi, Cranfill, Paula J., Greninger, Patricia, Lynch, Conor C., Benes, Cyril H., Lawrence, Harshani R., Reuther, Gary W., Lawrence, Nicholas J., Schönbrunn, Ernst
Publicado no Mol Cancer Ther (2017)

Ligand-mediated protein degradation reveals functional conservation among sequence variants of the CUL4-type E3 ligase substrate receptor cereblon

Por Akuffo, Afua A., Alontaga, Aileen Y., Metcalf, Rainer, Beatty, Matthew S., Becker, Andreas, McDaniel, Jessica M., Hesterberg, Rebecca S., Goodheart, William E., Gunawan, Steven, Ayaz, Muhammad, Yang, Yan, Karim, Md Rezaul, Orobello, Morgan E., Daniel, Kenyon, Guida, Wayne, Yoder, Jeffrey A., Rajadhyaksha, Anjali M., Schönbrunn, Ernst, Lawrence, Harshani R., Lawrence, Nicholas J., Epling-Burnette, Pearlie K.
Publicado no J Biol Chem (2018)