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Bifunctional building blocks in the Ugi-azide condensation reaction: A general strategy toward exploration of new molecular diversity
1,5-disubstituted tetrazoles are an important drug-like scaffold known for their ability to mimic the cis-amide bond conformation. The scaffold is readily accessible via substitution of the carboxylic acid component of the Ugi multi-component reaction (MCR) with TMSN(3) in what is herein denoted the...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3795786/ https://ncbi.nlm.nih.gov/pubmed/23912086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3ob40900g |
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