Exploring Ugi-Azide Four-Component Reaction Products for Broad-Spectrum Influenza Antivirals with a High Genetic Barrier to Drug Resistance

Influenza viruses are respiratory pathogens that are responsible for seasonal influenza and sporadic influenza pandemic. The therapeutic efficacy of current influenza vaccines and small molecule antiviral drugs is limited due to the emergence of multidrug-resistant influenza viruses. In response to...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Jiantao, Hu, Yanmei, Foley, Christopher, Wang, Yuanxiang, Musharrafieh, Rami, Xu, Shuting, Zhang, Yongtao, Ma, Chunlong, Hulme, Christopher, Wang, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854701/
https://ncbi.nlm.nih.gov/pubmed/29545578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22875-9
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