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Exploring Ugi-Azide Four-Component Reaction Products for Broad-Spectrum Influenza Antivirals with a High Genetic Barrier to Drug Resistance

Influenza viruses are respiratory pathogens that are responsible for seasonal influenza and sporadic influenza pandemic. The therapeutic efficacy of current influenza vaccines and small molecule antiviral drugs is limited due to the emergence of multidrug-resistant influenza viruses. In response to...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Zhang, Jiantao, Hu, Yanmei, Foley, Christopher, Wang, Yuanxiang, Musharrafieh, Rami, Xu, Shuting, Zhang, Yongtao, Ma, Chunlong, Hulme, Christopher, Wang, Jun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854701/
https://ncbi.nlm.nih.gov/pubmed/29545578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22875-9
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