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Chemical Genomics Approach Leads to the Identification of Hesperadin, an Aurora B Kinase Inhibitor, as a Broad-Spectrum Influenza Antiviral

Influenza viruses are respiratory pathogens that are responsible for annual influenza epidemics and sporadic influenza pandemics. Oseltamivir (Tamiflu(®)) is currently the only FDA-approved oral drug that is available for the prevention and treatment of influenza virus infection. However, its narrow...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Hu, Yanmei, Zhang, Jiantao, Musharrafieh, Rami, Hau, Raymond, Ma, Chunlong, Wang, Jun
Format: Artigo
Langue:Inglês
Publié: MDPI 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618578/
https://ncbi.nlm.nih.gov/pubmed/28885544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18091929
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