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Concise One-Pot Preparation of Unique Bis-Pyrrolidinone Tetrazoles

A one-pot, two-step synthesis of bis-pyrrolidinone tetrazoles has been established via the Ugi-Azide reaction using methyl levulinate, primary amines, isocyanides and azidotrimethylsilane with subsequent acid treatment to catalyze the lactam formation. The efficiency of the protocol was established...

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Autors principals: Gunawan, Steven, Petit, Joachim, Hulme, Christopher
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299871/
https://ncbi.nlm.nih.gov/pubmed/22330239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/co200209a
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