Concise Synthesis of Tetrazole Macrocycle

[Image: see text] A concise two step synthesis of tetrazole containing macrocycles from readily accessible starting materials is presented. The first step comprises a chemoselective amidation of amino acid derived isocyanocarboxylicacid esters with unprotected symmetrical diamines to afford diverse...

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Pubblicato in:Org Lett
Autori principali: Abdelraheem, Eman M. M., de Haan, Michel P., Patil, Pravin, Kurpiewska, Katarzyna, Kalinowska-Tłuścik, Justyna, Shaabani, Shabnam, Dömling, Alexander
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2017
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5633831/
https://ncbi.nlm.nih.gov/pubmed/28901777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b02319
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