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Concise Synthesis of Macrocycles by Multicomponent Reactions
A short reaction pathway was devised to synthesize a library of artificial 18–27-membered macrocycles. The five-step reaction sequence involves ring opening of a cyclic anhydride with a diamine, esterification, coupling with an amino acid isocyanide, saponification, and, finally, macro-ring closure...
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| Publicado no: | Synthesis (Stuttg) |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6706064/ https://ncbi.nlm.nih.gov/pubmed/31439965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0036-1590946 |
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