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Two-Step Macrocycle Synthesis by Classical Ugi Reaction
[Image: see text] The direct nonpeptidic macrocycle synthesis of α-isocyano-ω-amines via the classical Ugi four-component reaction (U-4CR) is introduced. Herein an efficient and flexible two-step procedure to complex macrocycles is reported. In the first step, the reaction between unprotected diamin...
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| Veröffentlicht in: | J Org Chem |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Chemical
Society
2018
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5799868/ https://ncbi.nlm.nih.gov/pubmed/29327924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.7b02984 |
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