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Macrocycles: MCR synthesis and applications in drug discovery

Macrocycles are an emerging and largely underexploited part of chemical space where potential drugs for difficult genomic targets can be discovered. Macro-cycles can have advantages over their natural twins such as better control over synthesis, physicochemical properties and target binding. Fast an...

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Podrobná bibliografie
Vydáno v:J Org Chem
Hlavní autoři: Abdelraheem, Eman M.M., Shaabani, Shabnam, Dömling, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6280654/
https://ncbi.nlm.nih.gov/pubmed/27598302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.6b01430
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