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Macrocycles: MCR synthesis and applications in drug discovery
Macrocycles are an emerging and largely underexploited part of chemical space where potential drugs for difficult genomic targets can be discovered. Macro-cycles can have advantages over their natural twins such as better control over synthesis, physicochemical properties and target binding. Fast an...
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| Publicado no: | J Org Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6280654/ https://ncbi.nlm.nih.gov/pubmed/27598302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.6b01430 |
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