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Identification of Synergistic, Clinically Achievable, Combination Therapies for Osteosarcoma
Systemic therapy has improved osteosarcoma event-free and overall survival, but 30–50% of patients originally diagnosed will have progressive or recurrent disease, which is difficult to cure. Osteosarcoma has a complex karyotype, with loss of p53 in the vast majority of cases and an absence of recur...
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Publicado no: | Sci Rep |
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Principais autores: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4658502/ https://ncbi.nlm.nih.gov/pubmed/26601688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16991 |
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