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Histone deacetylase inhibition prevents the growth of primary and metastatic osteosarcoma

Overall survival rates for patients with advanced osteosarcoma have remained static for over three decades. An in vitro analysis of osteosarcoma cell lines for sensitivity to an array of approved cancer therapies revealed that panobinostat, a broad spectrum histone deacetalyase (HDAC) inhibitor, is...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: McGuire, Jeremy J., Nerlakanti, Niveditha, Lo, Chen Hao, Tauro, Marilena, Utset-Ward, Thomas J., Reed, Damon R., Lynch, Conor C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7787271/
https://ncbi.nlm.nih.gov/pubmed/32599665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.33046
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