Histone Deacetylases and Histone Deacetylase Inhibitors in Neuroblastoma

Histone deacetylases (HDACs) are enzymes that play a key role in regulating gene expression by remodeling chromatin structure. An imbalance of histone acetylation caused by deregulated HDAC expression and activity is known to promote tumor progression in a number of tumor types, including neuroblast...

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Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Phimmachanh, Monica, Han, Jeremy Z. R., O’Donnell, Yolande E. I., Latham, Sharissa L., Croucher, David R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Cell and Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7575710/
https://ncbi.nlm.nih.gov/pubmed/33117806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.578770
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