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Ku70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors

Histone deacetylase inhibitors (HDACIs) are therapeutic drugs that inhibit deacetylase activity, thereby increasing acetylation of many proteins, including histones. HDACIs have antineoplastic effects in preclinical and clinical trials and are being considered for cancers with unmet therapeutic need...

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Hlavní autoři: Subramanian, Chitra, Opipari, Anthony W., Bian, Xin, Castle, Valerie P., Kwok, Roland P. S.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC555706/
https://ncbi.nlm.nih.gov/pubmed/15778293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408351102
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