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Ku70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors
Histone deacetylase inhibitors (HDACIs) are therapeutic drugs that inhibit deacetylase activity, thereby increasing acetylation of many proteins, including histones. HDACIs have antineoplastic effects in preclinical and clinical trials and are being considered for cancers with unmet therapeutic need...
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| Publicat a: | Proc Natl Acad Sci U S A |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC555706/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15778293/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0408351102 |
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