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CREB-binding protein regulates Ku70 acetylation in response to ionization radiation in neuroblastoma

Ku70 was originally described as an auto-antigen, but it also functions as DNA repair protein in the nucleus and as an anti-apoptotic protein by binding to Bax in the cytoplasm, blocking Bax-mediated cell death. In neuroblastoma (NB) cells, Ku70’s binding with Bax is regulated by Ku70 acetylation su...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Subramanian, Chitra, Hada, Manila, Opipari, Anthony W., Castle, Valerie P., Kwok, Roland P.S.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578981/
https://ncbi.nlm.nih.gov/pubmed/23223795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-12-0065
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