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Ku70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors

Histone deacetylase inhibitors (HDACIs) are therapeutic drugs that inhibit deacetylase activity, thereby increasing acetylation of many proteins, including histones. HDACIs have antineoplastic effects in preclinical and clinical trials and are being considered for cancers with unmet therapeutic need...

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Bibliografiske detaljer
Main Authors: Subramanian, Chitra, Opipari, Anthony W., Bian, Xin, Castle, Valerie P., Kwok, Roland P. S.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC555706/
https://ncbi.nlm.nih.gov/pubmed/15778293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408351102
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