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The Roles of Histone Deacetylases and Their Inhibitors in Cancer Therapy
Genetic mutations and abnormal gene regulation are key mechanisms underlying tumorigenesis. Nucleosomes, which consist of DNA wrapped around histone cores, represent the basic units of chromatin. The fifth amino group (N(ε)) of histone lysine residues is a common site for post-translational modifica...
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| Gepubliceerd in: | Front Cell Dev Biol |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Frontiers Media S.A.
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7552186/ https://ncbi.nlm.nih.gov/pubmed/33117804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.576946 |
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