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The Roles of Histone Deacetylases and Their Inhibitors in Cancer Therapy
Genetic mutations and abnormal gene regulation are key mechanisms underlying tumorigenesis. Nucleosomes, which consist of DNA wrapped around histone cores, represent the basic units of chromatin. The fifth amino group (N(ε)) of histone lysine residues is a common site for post-translational modifica...
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| Publicado no: | Front Cell Dev Biol |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7552186/ https://ncbi.nlm.nih.gov/pubmed/33117804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.576946 |
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