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The Roles of Histone Deacetylases and Their Inhibitors in Cancer Therapy
Genetic mutations and abnormal gene regulation are key mechanisms underlying tumorigenesis. Nucleosomes, which consist of DNA wrapped around histone cores, represent the basic units of chromatin. The fifth amino group (N(ε)) of histone lysine residues is a common site for post-translational modifica...
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| Veröffentlicht in: | Front Cell Dev Biol |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7552186/ https://ncbi.nlm.nih.gov/pubmed/33117804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.576946 |
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