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Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiation

The discovery of new small molecules and their testing in rational combination poses an ongoing problem for rare diseases, in particular, for pediatric cancers such as neuroblastoma. Despite maximal cytotoxic therapy with double autologous stem cell transplantation, outcome remains poor for children...

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Библиографические подробности
Главные авторы: Hahn, Cynthia K., Ross, Kenneth N., Warrington, Ian M., Mazitschek, Ralph, Kanegai, Cindy M., Wright, Renee D., Kung, Andrew L., Golub, Todd R., Stegmaier, Kimberly
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474517/
https://ncbi.nlm.nih.gov/pubmed/18607002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710413105
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