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Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiation

The discovery of new small molecules and their testing in rational combination poses an ongoing problem for rare diseases, in particular, for pediatric cancers such as neuroblastoma. Despite maximal cytotoxic therapy with double autologous stem cell transplantation, outcome remains poor for children...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hahn, Cynthia K., Ross, Kenneth N., Warrington, Ian M., Mazitschek, Ralph, Kanegai, Cindy M., Wright, Renee D., Kung, Andrew L., Golub, Todd R., Stegmaier, Kimberly
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474517/
https://ncbi.nlm.nih.gov/pubmed/18607002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710413105
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