Assessment of circulating tumor DNA in pediatric solid tumors: The promise of liquid biopsies

par Abbou, Samuel D., Shulman, David S., DuBois, Steven G., Crompton, Brian D.
Publié dans Pediatr Blood Cancer (2019)

Reversible severe combined immunodeficiency phenotype secondary to a mutation of the proton-coupled folate transporter

par Borzutzky, Arturo, Crompton, Brian, Bergmann, Anke K., Giliani, Silvia, Baxi, Sachin, Martin, Madelena, Neufeld, Ellis J., Notarangelo, Luigi D.
Publié 2009

Patient/parent perspectives on genomic tumor profiling of pediatric solid tumors: The Individualized Cancer Therapy (iCat) experience

par Marron, Jonathan M., DuBois, Steven G., Bender, Julia Glade, Kim, AeRang, Crompton, Brian D., Meyer, Stephanie C., Janeway, Katherine A., Mack, Jennifer W.
Publié dans Pediatr Blood Cancer (2016)

Blood collection in cell-stabilizing tubes does not impact germline DNA quality for pediatric patients

par Wollison, Bruce M., Thai, Edwin, Mckinney, Aimee, Ward, Abigail, Clapp, Andrea, Clinton, Catherine, Nag, Anwesha, Thorner, Aaron R., Gastier-Foster, Julie M., Crompton, Brian D.
Publié dans PLoS One (2017)

Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcoma

par Kennedy, Alyssa L., Vallurupalli, Mounica, Chen, Liying, Crompton, Brian, Cowley, Glenn, Vazquez, Francisca, Weir, Barbara A., Tsherniak, Aviad, Parasuraman, Sudha, Kim, Sunkyu, Alexe, Gabriela, Stegmaier, Kimberly
Publié dans Oncotarget (2015)

Duality of Purpose: Participant and Parent Understanding of the Purpose of Genomic Tumor Profiling Research Among Children and Young Adults With Solid Tumors

par Marron, Jonathan M., Cronin, Angel M., DuBois, Steven G., Glade-Bender, Julia, Kim, AeRang, Crompton, Brian D., Meyer, Stephanie C., Janeway, Katherine A., Mack, Jennifer W.
Publié dans JCO Precis Oncol (2019)

Detection of Circulating Tumor DNA in Patients With Leiomyosarcoma With Progressive Disease

par Hemming, Matthew L., Klega, Kelly, Rhoades, Justin, Ha, Gavin, Acker, Kate E., Andersen, Jessica L., Thai, Edwin, Nag, Anwesha, Thorner, Aaron R., Raut, Chandrajit P., George, Suzanne, Crompton, Brian D.
Publié dans JCO Precis Oncol (2019)

EWS–FLI1 modulated alternative splicing of ARID1A reveals novel oncogenic function through the BAF complex

par Selvanathan, Saravana P, Graham, Garrett T, Grego, Alexander R, Baker, Tabari M, Hogg, J Robert, Simpson, Mark, Batish, Mona, Crompton, Brian, Stegmaier, Kimberly, Tomazou, Eleni M, Kovar, Heinrich, Üren, Aykut, Toretsky, Jeffrey A
Publié dans Nucleic Acids Res (2019)

Detection of Somatic Structural Variants Enables Quantification and Characterization of Circulating Tumor DNA in Children With Solid Tumors

par Klega, Kelly, Imamovic-Tuco, Alma, Ha, Gavin, Clapp, Andrea N., Meyer, Stephanie, Ward, Abigail, Clinton, Catherine, Nag, Anwesha, Van Allen, Eliezer, Mullen, Elizabeth, DuBois, Steven G., Janeway, Katherine, Meyerson, Matthew, Thorner, Aaron R., Crompton, Brian D.
Publié dans JCO Precis Oncol (2018)

Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis

par Marques Howarth, Michelle, Simpson, David, Ngok, Siu P., Nieves, Bethsaida, Chen, Ron, Siprashvili, Zurab, Vaka, Dedeepya, Breese, Marcus R., Crompton, Brian D., Alexe, Gabriela, Hawkins, Doug S., Jacobson, Damon, Brunner, Alayne L., West, Robert, Mora, Jaume, Stegmaier, Kimberly, Khavari, Paul, Sweet-Cordero, E. Alejandro
Publié dans J Clin Invest (2014)

Therapeutic targeting of KDM1A/LSD1 in Ewing sarcoma with SP-2509 engages the endoplasmic reticulum stress response

par Pishas, Kathleen I., Drenberg, Christina D., Taslim, Cenny, Theisen, Emily R., Johnson, Kirsten M., Saund, Ranajeet S., Pop, Ioana L, Crompton, Brian D., Lawlor, Elizabeth R, Tirode, Franck, Mora, Jaume, Delattre, Olivier, Beckerle, Mary C., Callen, David F., Sharma, Sunil, Lessnick., Stephen L.
Publié dans Mol Cancer Ther (2018)

Provocative Questions in osteosarcoma basic and translational biology: a report from the Children’s Oncology Group

par Roberts, Ryan D., Lizardo, Michael M., Reed, Damon R., Hingorani, Pooja, Glover, Jason, Allen-Rhoades, Wendy, Fan, Timothy, Khanna, Chand, Sweet-Cordero, E. Alejandro, Cash, Thomas, Bishop, Michael W., Hegde, Meenakshi, Sertil, Aparna R., Koelsche, Christian, Mirabello, Lisa, Malkin, David, Sorensen, Poul H., Meltzer, Paul S., Janeway, Katherine A., Gorlick, Richard, Crompton, Brian D.
Publié dans Cancer (2019)

Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children’s Oncology Group

par Shulman, David S., Klega, Kelly, Imamovic-Tuco, Alma, Clapp, Andrea, Nag, Anwesha, Thorner, Aaron R., Van Allen, Eliezer, Ha, Gavin, Lessnick, Stephen L., Gorlick, Richard, Janeway, Katherine A., Leavey, Patrick J., Mascarenhas, Leo, London, Wendy B., Vo, Kieuhoa T., Stegmaier, Kimberly, Hall, David, Krailo, Mark D., Barkauskas, Donald A., DuBois, Steven G., Crompton, Brian D.
Publié dans Br J Cancer (2018)

Correction: Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children’s Oncology Group

par Shulman, David S., Klega, Kelly, Imamovic-Tuco, Alma, Clapp, Andrea, Nag, Anwesha, Thorner, Aaron R., Van Allen, Eliezer, Ha, Gavin, Lessnick, Stephen L., Gorlick, Richard, Janeway, Katherine A., Leavey, Patrick J., Mascarenhas, Leo, London, Wendy B., Vo, Kieuhoa T., Stegmaier, Kimberly, Hall, David, Krailo, Mark D., Barkauskas, Donald A., DuBois, Steven G., Crompton, Brian D.
Publié dans Br J Cancer (2019)

High-throughput Chemical Screening Identifies Focal Adhesion Kinase and Aurora Kinase B Inhibition as a Synergistic Treatment Combination in Ewing Sarcoma

par Wang, Sarah, Hwang, Elizabeth E., Guha, Rajarshi, O’Neill, Allison F., Melong, Nicole, Veinotte, Chansey J., Saur, Amy Conway, Wuerthele, Kellsey, Shen, Min, McKnight, Crystal, Alexe, Gabriela, Lemieux, Madeleine E., Wang, Amy, Hughes, Emma, Xu, Xin, Boxer, Matthew B., Hall, Matthew D., Kung, Andrew, Berman, Jason N., Davis, Mindy I., Stegmaier, Kimberly, Crompton, Brian D.
Publié dans Clin Cancer Res (2019)

Current State of Pediatric Sarcoma Biology and Opportunities for Future Discovery: A Report from the Sarcoma Translational Research Workshop

par Hingorani, Pooja, Janeway, Katherine, Crompton, Brian D., Kadoch, Cigall, Mackall, Crystal L., Khan, Javed, Shern, Jack F., Schiffman, Joshua, Mirabello, Lisa, Savage, Sharon A., Ladanyi, Marc, Meltzer, Paul, Bult, Carol J., Adamson, Peter C., Lupo, Philip J., Mody, Rajen, DuBois, Steven G., Parsons, D. Williams, Khanna, Chand, Lau, Ching, Hawkins, Douglas S., Randall, R. Lor, Smith, Malcolm, Sorensen, Poul H., Plon, Sharon E., Skapek, Stephen X., Lessnick, Stephen, Gorlick, Richard, Reed, Damon R.
Publié dans Cancer Genet (2016)

Integrated genetic and pharmacologic interrogation of rare cancers

par Hong, Andrew L., Tseng, Yuen-Yi, Cowley, Glenn S., Jonas, Oliver, Cheah, Jaime H., Kynnap, Bryan D., Doshi, Mihir B., Oh, Coyin, Meyer, Stephanie C., Church, Alanna J., Gill, Shubhroz, Bielski, Craig M., Keskula, Paula, Imamovic, Alma, Howell, Sara, Kryukov, Gregory V., Clemons, Paul A., Tsherniak, Aviad, Vazquez, Francisca, Crompton, Brian D., Shamji, Alykhan F., Rodriguez-Galindo, Carlos, Janeway, Katherine A., Roberts, Charles W. M., Stegmaier, Kimberly, van Hummelen, Paul, Cima, Michael J., Langer, Robert S., Garraway, Levi A., Schreiber, Stuart L., Root, David E., Hahn, William C., Boehm, Jesse S.
Publié dans Nat Commun (2016)

Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition

par Hong, Andrew L, Tseng, Yuen-Yi, Wala, Jeremiah A, Kim, Won-Jun, Kynnap, Bryan D, Doshi, Mihir B, Kugener, Guillaume, Sandoval, Gabriel J, Howard, Thomas P, Li, Ji, Yang, Xiaoping, Tillgren, Michelle, Ghandi, Mahmhoud, Sayeed, Abeer, Deasy, Rebecca, Ward, Abigail, McSteen, Brian, Labella, Katherine M, Keskula, Paula, Tracy, Adam, Connor, Cora, Clinton, Catherine M, Church, Alanna J, Crompton, Brian D, Janeway, Katherine A, Van Hare, Barbara, Sandak, David, Gjoerup, Ole, Bandopadhayay, Pratiti, Clemons, Paul A, Schreiber, Stuart L, Root, David E, Gokhale, Prafulla C, Chi, Susan N, Mullen, Elizabeth A, Roberts, Charles WM, Kadoch, Cigall, Beroukhim, Rameen, Ligon, Keith L, Boehm, Jesse S, Hahn, William C
Publié dans eLife (2019)

Mutational heterogeneity in cancer and the search for new cancer genes

par Lawrence, Michael S., Stojanov, Petar, Polak, Paz, Kryukov, Gregory V., Cibulskis, Kristian, Sivachenko, Andrey, Carter, Scott L., Stewart, Chip, Mermel, Craig H., Roberts, Steven A., Kiezun, Adam, Hammerman, Peter S., McKenna, Aaron, Drier, Yotam, Zou, Lihua, Ramos, Alex H., Pugh, Trevor J., Stransky, Nicolas, Helman, Elena, Kim, Jaegil, Sougnez, Carrie, Ambrogio, Lauren, Nickerson, Elizabeth, Shefler, Erica, Cortés, Maria L., Auclair, Daniel, Saksena, Gordon, Voet, Douglas, Noble, Michael, DiCara, Daniel, Lin, Pei, Lichtenstein, Lee, Heiman, David I., Fennell, Timothy, Imielinski, Marcin, Hernandez, Bryan, Hodis, Eran, Baca, Sylvan, Dulak, Austin M., Lohr, Jens, Landau, Dan-Avi, Wu, Catherine J., Melendez-Zajgla, Jorge, Hidalgo-Miranda, Alfredo, Koren, Amnon, McCarroll, Steven A., Mora, Jaume, Crompton, Brian, Onofrio, Robert, Parkin, Melissa, Winckler, Wendy, Ardlie, Kristin, Gabriel, Stacey B., Roberts, Charles W. M., Biegel, Jaclyn A., Stegmaier, Kimberly, Bass, Adam J., Garraway, Levi A., Meyerson, Matthew, Golub, Todd R., Gordenin, Dmitry A., Sunyaev, Shamil, Lander, Eric S., Getz, Gad
Publié 2013