Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcoma

Ewing sarcoma is an aggressive bone and soft tissue tumor in children and adolescents, with treatment remaining a clinical challenge. This disease is mediated by somatic chromosomal translocations of the EWS gene and a gene encoding an ETS transcription factor, most commonly, FLI1. While direct targ...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kennedy, Alyssa L., Vallurupalli, Mounica, Chen, Liying, Crompton, Brian, Cowley, Glenn, Vazquez, Francisca, Weir, Barbara A., Tsherniak, Aviad, Parasuraman, Sudha, Kim, Sunkyu, Alexe, Gabriela, Stegmaier, Kimberly
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745789/
https://ncbi.nlm.nih.gov/pubmed/26337082
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados