Assessment of circulating tumor DNA in pediatric solid tumors: The promise of liquid biopsies

Por Abbou, Samuel D., Shulman, David S., DuBois, Steven G., Crompton, Brian D.
Publicado no Pediatr Blood Cancer (2019)

Reversible severe combined immunodeficiency phenotype secondary to a mutation of the proton-coupled folate transporter

Por Borzutzky, Arturo, Crompton, Brian, Bergmann, Anke K., Giliani, Silvia, Baxi, Sachin, Martin, Madelena, Neufeld, Ellis J., Notarangelo, Luigi D.
Publicado em 2009

Patient/parent perspectives on genomic tumor profiling of pediatric solid tumors: The Individualized Cancer Therapy (iCat) experience

Por Marron, Jonathan M., DuBois, Steven G., Bender, Julia Glade, Kim, AeRang, Crompton, Brian D., Meyer, Stephanie C., Janeway, Katherine A., Mack, Jennifer W.
Publicado no Pediatr Blood Cancer (2016)

Blood collection in cell-stabilizing tubes does not impact germline DNA quality for pediatric patients

Por Wollison, Bruce M., Thai, Edwin, Mckinney, Aimee, Ward, Abigail, Clapp, Andrea, Clinton, Catherine, Nag, Anwesha, Thorner, Aaron R., Gastier-Foster, Julie M., Crompton, Brian D.
Publicado no PLoS One (2017)

Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcoma

Por Kennedy, Alyssa L., Vallurupalli, Mounica, Chen, Liying, Crompton, Brian, Cowley, Glenn, Vazquez, Francisca, Weir, Barbara A., Tsherniak, Aviad, Parasuraman, Sudha, Kim, Sunkyu, Alexe, Gabriela, Stegmaier, Kimberly
Publicado no Oncotarget (2015)

Duality of Purpose: Participant and Parent Understanding of the Purpose of Genomic Tumor Profiling Research Among Children and Young Adults With Solid Tumors

Por Marron, Jonathan M., Cronin, Angel M., DuBois, Steven G., Glade-Bender, Julia, Kim, AeRang, Crompton, Brian D., Meyer, Stephanie C., Janeway, Katherine A., Mack, Jennifer W.
Publicado no JCO Precis Oncol (2019)

Detection of Circulating Tumor DNA in Patients With Leiomyosarcoma With Progressive Disease

Por Hemming, Matthew L., Klega, Kelly, Rhoades, Justin, Ha, Gavin, Acker, Kate E., Andersen, Jessica L., Thai, Edwin, Nag, Anwesha, Thorner, Aaron R., Raut, Chandrajit P., George, Suzanne, Crompton, Brian D.
Publicado no JCO Precis Oncol (2019)

EWS–FLI1 modulated alternative splicing of ARID1A reveals novel oncogenic function through the BAF complex

Por Selvanathan, Saravana P, Graham, Garrett T, Grego, Alexander R, Baker, Tabari M, Hogg, J Robert, Simpson, Mark, Batish, Mona, Crompton, Brian, Stegmaier, Kimberly, Tomazou, Eleni M, Kovar, Heinrich, Üren, Aykut, Toretsky, Jeffrey A
Publicado no Nucleic Acids Res (2019)

Detection of Somatic Structural Variants Enables Quantification and Characterization of Circulating Tumor DNA in Children With Solid Tumors

Por Klega, Kelly, Imamovic-Tuco, Alma, Ha, Gavin, Clapp, Andrea N., Meyer, Stephanie, Ward, Abigail, Clinton, Catherine, Nag, Anwesha, Van Allen, Eliezer, Mullen, Elizabeth, DuBois, Steven G., Janeway, Katherine, Meyerson, Matthew, Thorner, Aaron R., Crompton, Brian D.
Publicado no JCO Precis Oncol (2018)

Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis

Por Marques Howarth, Michelle, Simpson, David, Ngok, Siu P., Nieves, Bethsaida, Chen, Ron, Siprashvili, Zurab, Vaka, Dedeepya, Breese, Marcus R., Crompton, Brian D., Alexe, Gabriela, Hawkins, Doug S., Jacobson, Damon, Brunner, Alayne L., West, Robert, Mora, Jaume, Stegmaier, Kimberly, Khavari, Paul, Sweet-Cordero, E. Alejandro
Publicado no J Clin Invest (2014)

Therapeutic targeting of KDM1A/LSD1 in Ewing sarcoma with SP-2509 engages the endoplasmic reticulum stress response

Por Pishas, Kathleen I., Drenberg, Christina D., Taslim, Cenny, Theisen, Emily R., Johnson, Kirsten M., Saund, Ranajeet S., Pop, Ioana L, Crompton, Brian D., Lawlor, Elizabeth R, Tirode, Franck, Mora, Jaume, Delattre, Olivier, Beckerle, Mary C., Callen, David F., Sharma, Sunil, Lessnick., Stephen L.
Publicado no Mol Cancer Ther (2018)

Provocative Questions in osteosarcoma basic and translational biology: a report from the Children’s Oncology Group

Por Roberts, Ryan D., Lizardo, Michael M., Reed, Damon R., Hingorani, Pooja, Glover, Jason, Allen-Rhoades, Wendy, Fan, Timothy, Khanna, Chand, Sweet-Cordero, E. Alejandro, Cash, Thomas, Bishop, Michael W., Hegde, Meenakshi, Sertil, Aparna R., Koelsche, Christian, Mirabello, Lisa, Malkin, David, Sorensen, Poul H., Meltzer, Paul S., Janeway, Katherine A., Gorlick, Richard, Crompton, Brian D.
Publicado no Cancer (2019)

Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children’s Oncology Group

Por Shulman, David S., Klega, Kelly, Imamovic-Tuco, Alma, Clapp, Andrea, Nag, Anwesha, Thorner, Aaron R., Van Allen, Eliezer, Ha, Gavin, Lessnick, Stephen L., Gorlick, Richard, Janeway, Katherine A., Leavey, Patrick J., Mascarenhas, Leo, London, Wendy B., Vo, Kieuhoa T., Stegmaier, Kimberly, Hall, David, Krailo, Mark D., Barkauskas, Donald A., DuBois, Steven G., Crompton, Brian D.
Publicado no Br J Cancer (2018)

Correction: Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children’s Oncology Group

Por Shulman, David S., Klega, Kelly, Imamovic-Tuco, Alma, Clapp, Andrea, Nag, Anwesha, Thorner, Aaron R., Van Allen, Eliezer, Ha, Gavin, Lessnick, Stephen L., Gorlick, Richard, Janeway, Katherine A., Leavey, Patrick J., Mascarenhas, Leo, London, Wendy B., Vo, Kieuhoa T., Stegmaier, Kimberly, Hall, David, Krailo, Mark D., Barkauskas, Donald A., DuBois, Steven G., Crompton, Brian D.
Publicado no Br J Cancer (2019)

High-throughput Chemical Screening Identifies Focal Adhesion Kinase and Aurora Kinase B Inhibition as a Synergistic Treatment Combination in Ewing Sarcoma

Por Wang, Sarah, Hwang, Elizabeth E., Guha, Rajarshi, O’Neill, Allison F., Melong, Nicole, Veinotte, Chansey J., Saur, Amy Conway, Wuerthele, Kellsey, Shen, Min, McKnight, Crystal, Alexe, Gabriela, Lemieux, Madeleine E., Wang, Amy, Hughes, Emma, Xu, Xin, Boxer, Matthew B., Hall, Matthew D., Kung, Andrew, Berman, Jason N., Davis, Mindy I., Stegmaier, Kimberly, Crompton, Brian D.
Publicado no Clin Cancer Res (2019)

Current State of Pediatric Sarcoma Biology and Opportunities for Future Discovery: A Report from the Sarcoma Translational Research Workshop

Por Hingorani, Pooja, Janeway, Katherine, Crompton, Brian D., Kadoch, Cigall, Mackall, Crystal L., Khan, Javed, Shern, Jack F., Schiffman, Joshua, Mirabello, Lisa, Savage, Sharon A., Ladanyi, Marc, Meltzer, Paul, Bult, Carol J., Adamson, Peter C., Lupo, Philip J., Mody, Rajen, DuBois, Steven G., Parsons, D. Williams, Khanna, Chand, Lau, Ching, Hawkins, Douglas S., Randall, R. Lor, Smith, Malcolm, Sorensen, Poul H., Plon, Sharon E., Skapek, Stephen X., Lessnick, Stephen, Gorlick, Richard, Reed, Damon R.
Publicado no Cancer Genet (2016)

Integrated genetic and pharmacologic interrogation of rare cancers

Por Hong, Andrew L., Tseng, Yuen-Yi, Cowley, Glenn S., Jonas, Oliver, Cheah, Jaime H., Kynnap, Bryan D., Doshi, Mihir B., Oh, Coyin, Meyer, Stephanie C., Church, Alanna J., Gill, Shubhroz, Bielski, Craig M., Keskula, Paula, Imamovic, Alma, Howell, Sara, Kryukov, Gregory V., Clemons, Paul A., Tsherniak, Aviad, Vazquez, Francisca, Crompton, Brian D., Shamji, Alykhan F., Rodriguez-Galindo, Carlos, Janeway, Katherine A., Roberts, Charles W. M., Stegmaier, Kimberly, van Hummelen, Paul, Cima, Michael J., Langer, Robert S., Garraway, Levi A., Schreiber, Stuart L., Root, David E., Hahn, William C., Boehm, Jesse S.
Publicado no Nat Commun (2016)

Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition

Por Hong, Andrew L, Tseng, Yuen-Yi, Wala, Jeremiah A, Kim, Won-Jun, Kynnap, Bryan D, Doshi, Mihir B, Kugener, Guillaume, Sandoval, Gabriel J, Howard, Thomas P, Li, Ji, Yang, Xiaoping, Tillgren, Michelle, Ghandi, Mahmhoud, Sayeed, Abeer, Deasy, Rebecca, Ward, Abigail, McSteen, Brian, Labella, Katherine M, Keskula, Paula, Tracy, Adam, Connor, Cora, Clinton, Catherine M, Church, Alanna J, Crompton, Brian D, Janeway, Katherine A, Van Hare, Barbara, Sandak, David, Gjoerup, Ole, Bandopadhayay, Pratiti, Clemons, Paul A, Schreiber, Stuart L, Root, David E, Gokhale, Prafulla C, Chi, Susan N, Mullen, Elizabeth A, Roberts, Charles WM, Kadoch, Cigall, Beroukhim, Rameen, Ligon, Keith L, Boehm, Jesse S, Hahn, William C
Publicado no eLife (2019)

Mutational heterogeneity in cancer and the search for new cancer genes

Por Lawrence, Michael S., Stojanov, Petar, Polak, Paz, Kryukov, Gregory V., Cibulskis, Kristian, Sivachenko, Andrey, Carter, Scott L., Stewart, Chip, Mermel, Craig H., Roberts, Steven A., Kiezun, Adam, Hammerman, Peter S., McKenna, Aaron, Drier, Yotam, Zou, Lihua, Ramos, Alex H., Pugh, Trevor J., Stransky, Nicolas, Helman, Elena, Kim, Jaegil, Sougnez, Carrie, Ambrogio, Lauren, Nickerson, Elizabeth, Shefler, Erica, Cortés, Maria L., Auclair, Daniel, Saksena, Gordon, Voet, Douglas, Noble, Michael, DiCara, Daniel, Lin, Pei, Lichtenstein, Lee, Heiman, David I., Fennell, Timothy, Imielinski, Marcin, Hernandez, Bryan, Hodis, Eran, Baca, Sylvan, Dulak, Austin M., Lohr, Jens, Landau, Dan-Avi, Wu, Catherine J., Melendez-Zajgla, Jorge, Hidalgo-Miranda, Alfredo, Koren, Amnon, McCarroll, Steven A., Mora, Jaume, Crompton, Brian, Onofrio, Robert, Parkin, Melissa, Winckler, Wendy, Ardlie, Kristin, Gabriel, Stacey B., Roberts, Charles W. M., Biegel, Jaclyn A., Stegmaier, Kimberly, Bass, Adam J., Garraway, Levi A., Meyerson, Matthew, Golub, Todd R., Gordenin, Dmitry A., Sunyaev, Shamil, Lander, Eric S., Getz, Gad
Publicado em 2013