Detection of Somatic Structural Variants Enables Quantification and Characterization of Circulating Tumor DNA in Children With Solid Tumors

OBJECTIVE: Liquid biopsies are being rapidly used in adult cancers as new biomarkers of disease. Circulating tumor DNA (ctDNA) levels have been reported to be proportional to disease burden, correlate with treatment response, and predict relapse. However, little is known about how frequently ctDNA i...

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Detalhes bibliográficos
Publicado no:JCO Precis Oncol
Main Authors: Klega, Kelly, Imamovic-Tuco, Alma, Ha, Gavin, Clapp, Andrea N., Meyer, Stephanie, Ward, Abigail, Clinton, Catherine, Nag, Anwesha, Van Allen, Eliezer, Mullen, Elizabeth, DuBois, Steven G., Janeway, Katherine, Meyerson, Matthew, Thorner, Aaron R., Crompton, Brian D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2018
Assuntos:
Original Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6049092/
https://ncbi.nlm.nih.gov/pubmed/30027144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.17.00285
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