Assessment of circulating tumor DNA in pediatric solid tumors: The promise of liquid biopsies

Autor Abbou, Samuel D., Shulman, David S., DuBois, Steven G., Crompton, Brian D.
Vydáno v Pediatr Blood Cancer (2019)

Reversible severe combined immunodeficiency phenotype secondary to a mutation of the proton-coupled folate transporter

Autor Borzutzky, Arturo, Crompton, Brian, Bergmann, Anke K., Giliani, Silvia, Baxi, Sachin, Martin, Madelena, Neufeld, Ellis J., Notarangelo, Luigi D.
Vydáno 2009

Patient/parent perspectives on genomic tumor profiling of pediatric solid tumors: The Individualized Cancer Therapy (iCat) experience

Autor Marron, Jonathan M., DuBois, Steven G., Bender, Julia Glade, Kim, AeRang, Crompton, Brian D., Meyer, Stephanie C., Janeway, Katherine A., Mack, Jennifer W.
Vydáno v Pediatr Blood Cancer (2016)

Blood collection in cell-stabilizing tubes does not impact germline DNA quality for pediatric patients

Autor Wollison, Bruce M., Thai, Edwin, Mckinney, Aimee, Ward, Abigail, Clapp, Andrea, Clinton, Catherine, Nag, Anwesha, Thorner, Aaron R., Gastier-Foster, Julie M., Crompton, Brian D.
Vydáno v PLoS One (2017)

Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcoma

Autor Kennedy, Alyssa L., Vallurupalli, Mounica, Chen, Liying, Crompton, Brian, Cowley, Glenn, Vazquez, Francisca, Weir, Barbara A., Tsherniak, Aviad, Parasuraman, Sudha, Kim, Sunkyu, Alexe, Gabriela, Stegmaier, Kimberly
Vydáno v Oncotarget (2015)

Duality of Purpose: Participant and Parent Understanding of the Purpose of Genomic Tumor Profiling Research Among Children and Young Adults With Solid Tumors

Autor Marron, Jonathan M., Cronin, Angel M., DuBois, Steven G., Glade-Bender, Julia, Kim, AeRang, Crompton, Brian D., Meyer, Stephanie C., Janeway, Katherine A., Mack, Jennifer W.
Vydáno v JCO Precis Oncol (2019)

Detection of Circulating Tumor DNA in Patients With Leiomyosarcoma With Progressive Disease

Autor Hemming, Matthew L., Klega, Kelly, Rhoades, Justin, Ha, Gavin, Acker, Kate E., Andersen, Jessica L., Thai, Edwin, Nag, Anwesha, Thorner, Aaron R., Raut, Chandrajit P., George, Suzanne, Crompton, Brian D.
Vydáno v JCO Precis Oncol (2019)

EWS–FLI1 modulated alternative splicing of ARID1A reveals novel oncogenic function through the BAF complex

Autor Selvanathan, Saravana P, Graham, Garrett T, Grego, Alexander R, Baker, Tabari M, Hogg, J Robert, Simpson, Mark, Batish, Mona, Crompton, Brian, Stegmaier, Kimberly, Tomazou, Eleni M, Kovar, Heinrich, Üren, Aykut, Toretsky, Jeffrey A
Vydáno v Nucleic Acids Res (2019)

Detection of Somatic Structural Variants Enables Quantification and Characterization of Circulating Tumor DNA in Children With Solid Tumors

Autor Klega, Kelly, Imamovic-Tuco, Alma, Ha, Gavin, Clapp, Andrea N., Meyer, Stephanie, Ward, Abigail, Clinton, Catherine, Nag, Anwesha, Van Allen, Eliezer, Mullen, Elizabeth, DuBois, Steven G., Janeway, Katherine, Meyerson, Matthew, Thorner, Aaron R., Crompton, Brian D.
Vydáno v JCO Precis Oncol (2018)

Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis

Autor Marques Howarth, Michelle, Simpson, David, Ngok, Siu P., Nieves, Bethsaida, Chen, Ron, Siprashvili, Zurab, Vaka, Dedeepya, Breese, Marcus R., Crompton, Brian D., Alexe, Gabriela, Hawkins, Doug S., Jacobson, Damon, Brunner, Alayne L., West, Robert, Mora, Jaume, Stegmaier, Kimberly, Khavari, Paul, Sweet-Cordero, E. Alejandro
Vydáno v J Clin Invest (2014)

Therapeutic targeting of KDM1A/LSD1 in Ewing sarcoma with SP-2509 engages the endoplasmic reticulum stress response

Autor Pishas, Kathleen I., Drenberg, Christina D., Taslim, Cenny, Theisen, Emily R., Johnson, Kirsten M., Saund, Ranajeet S., Pop, Ioana L, Crompton, Brian D., Lawlor, Elizabeth R, Tirode, Franck, Mora, Jaume, Delattre, Olivier, Beckerle, Mary C., Callen, David F., Sharma, Sunil, Lessnick., Stephen L.
Vydáno v Mol Cancer Ther (2018)

Provocative Questions in osteosarcoma basic and translational biology: a report from the Children’s Oncology Group

Autor Roberts, Ryan D., Lizardo, Michael M., Reed, Damon R., Hingorani, Pooja, Glover, Jason, Allen-Rhoades, Wendy, Fan, Timothy, Khanna, Chand, Sweet-Cordero, E. Alejandro, Cash, Thomas, Bishop, Michael W., Hegde, Meenakshi, Sertil, Aparna R., Koelsche, Christian, Mirabello, Lisa, Malkin, David, Sorensen, Poul H., Meltzer, Paul S., Janeway, Katherine A., Gorlick, Richard, Crompton, Brian D.
Vydáno v Cancer (2019)

Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children’s Oncology Group

Autor Shulman, David S., Klega, Kelly, Imamovic-Tuco, Alma, Clapp, Andrea, Nag, Anwesha, Thorner, Aaron R., Van Allen, Eliezer, Ha, Gavin, Lessnick, Stephen L., Gorlick, Richard, Janeway, Katherine A., Leavey, Patrick J., Mascarenhas, Leo, London, Wendy B., Vo, Kieuhoa T., Stegmaier, Kimberly, Hall, David, Krailo, Mark D., Barkauskas, Donald A., DuBois, Steven G., Crompton, Brian D.
Vydáno v Br J Cancer (2018)

Correction: Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children’s Oncology Group

Autor Shulman, David S., Klega, Kelly, Imamovic-Tuco, Alma, Clapp, Andrea, Nag, Anwesha, Thorner, Aaron R., Van Allen, Eliezer, Ha, Gavin, Lessnick, Stephen L., Gorlick, Richard, Janeway, Katherine A., Leavey, Patrick J., Mascarenhas, Leo, London, Wendy B., Vo, Kieuhoa T., Stegmaier, Kimberly, Hall, David, Krailo, Mark D., Barkauskas, Donald A., DuBois, Steven G., Crompton, Brian D.
Vydáno v Br J Cancer (2019)

High-throughput Chemical Screening Identifies Focal Adhesion Kinase and Aurora Kinase B Inhibition as a Synergistic Treatment Combination in Ewing Sarcoma

Autor Wang, Sarah, Hwang, Elizabeth E., Guha, Rajarshi, O’Neill, Allison F., Melong, Nicole, Veinotte, Chansey J., Saur, Amy Conway, Wuerthele, Kellsey, Shen, Min, McKnight, Crystal, Alexe, Gabriela, Lemieux, Madeleine E., Wang, Amy, Hughes, Emma, Xu, Xin, Boxer, Matthew B., Hall, Matthew D., Kung, Andrew, Berman, Jason N., Davis, Mindy I., Stegmaier, Kimberly, Crompton, Brian D.
Vydáno v Clin Cancer Res (2019)

Current State of Pediatric Sarcoma Biology and Opportunities for Future Discovery: A Report from the Sarcoma Translational Research Workshop

Autor Hingorani, Pooja, Janeway, Katherine, Crompton, Brian D., Kadoch, Cigall, Mackall, Crystal L., Khan, Javed, Shern, Jack F., Schiffman, Joshua, Mirabello, Lisa, Savage, Sharon A., Ladanyi, Marc, Meltzer, Paul, Bult, Carol J., Adamson, Peter C., Lupo, Philip J., Mody, Rajen, DuBois, Steven G., Parsons, D. Williams, Khanna, Chand, Lau, Ching, Hawkins, Douglas S., Randall, R. Lor, Smith, Malcolm, Sorensen, Poul H., Plon, Sharon E., Skapek, Stephen X., Lessnick, Stephen, Gorlick, Richard, Reed, Damon R.
Vydáno v Cancer Genet (2016)

Integrated genetic and pharmacologic interrogation of rare cancers

Autor Hong, Andrew L., Tseng, Yuen-Yi, Cowley, Glenn S., Jonas, Oliver, Cheah, Jaime H., Kynnap, Bryan D., Doshi, Mihir B., Oh, Coyin, Meyer, Stephanie C., Church, Alanna J., Gill, Shubhroz, Bielski, Craig M., Keskula, Paula, Imamovic, Alma, Howell, Sara, Kryukov, Gregory V., Clemons, Paul A., Tsherniak, Aviad, Vazquez, Francisca, Crompton, Brian D., Shamji, Alykhan F., Rodriguez-Galindo, Carlos, Janeway, Katherine A., Roberts, Charles W. M., Stegmaier, Kimberly, van Hummelen, Paul, Cima, Michael J., Langer, Robert S., Garraway, Levi A., Schreiber, Stuart L., Root, David E., Hahn, William C., Boehm, Jesse S.
Vydáno v Nat Commun (2016)

Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition

Autor Hong, Andrew L, Tseng, Yuen-Yi, Wala, Jeremiah A, Kim, Won-Jun, Kynnap, Bryan D, Doshi, Mihir B, Kugener, Guillaume, Sandoval, Gabriel J, Howard, Thomas P, Li, Ji, Yang, Xiaoping, Tillgren, Michelle, Ghandi, Mahmhoud, Sayeed, Abeer, Deasy, Rebecca, Ward, Abigail, McSteen, Brian, Labella, Katherine M, Keskula, Paula, Tracy, Adam, Connor, Cora, Clinton, Catherine M, Church, Alanna J, Crompton, Brian D, Janeway, Katherine A, Van Hare, Barbara, Sandak, David, Gjoerup, Ole, Bandopadhayay, Pratiti, Clemons, Paul A, Schreiber, Stuart L, Root, David E, Gokhale, Prafulla C, Chi, Susan N, Mullen, Elizabeth A, Roberts, Charles WM, Kadoch, Cigall, Beroukhim, Rameen, Ligon, Keith L, Boehm, Jesse S, Hahn, William C
Vydáno v eLife (2019)

Mutational heterogeneity in cancer and the search for new cancer genes

Autor Lawrence, Michael S., Stojanov, Petar, Polak, Paz, Kryukov, Gregory V., Cibulskis, Kristian, Sivachenko, Andrey, Carter, Scott L., Stewart, Chip, Mermel, Craig H., Roberts, Steven A., Kiezun, Adam, Hammerman, Peter S., McKenna, Aaron, Drier, Yotam, Zou, Lihua, Ramos, Alex H., Pugh, Trevor J., Stransky, Nicolas, Helman, Elena, Kim, Jaegil, Sougnez, Carrie, Ambrogio, Lauren, Nickerson, Elizabeth, Shefler, Erica, Cortés, Maria L., Auclair, Daniel, Saksena, Gordon, Voet, Douglas, Noble, Michael, DiCara, Daniel, Lin, Pei, Lichtenstein, Lee, Heiman, David I., Fennell, Timothy, Imielinski, Marcin, Hernandez, Bryan, Hodis, Eran, Baca, Sylvan, Dulak, Austin M., Lohr, Jens, Landau, Dan-Avi, Wu, Catherine J., Melendez-Zajgla, Jorge, Hidalgo-Miranda, Alfredo, Koren, Amnon, McCarroll, Steven A., Mora, Jaume, Crompton, Brian, Onofrio, Robert, Parkin, Melissa, Winckler, Wendy, Ardlie, Kristin, Gabriel, Stacey B., Roberts, Charles W. M., Biegel, Jaclyn A., Stegmaier, Kimberly, Bass, Adam J., Garraway, Levi A., Meyerson, Matthew, Golub, Todd R., Gordenin, Dmitry A., Sunyaev, Shamil, Lander, Eric S., Getz, Gad
Vydáno 2013